摘要
目的观察在心力衰竭疾病治疗中重组人脑利钠肽联合益气复脉注射液治疗法的应用效果。方法心力衰竭患者数量为92例,就诊时间为2019年9月至2022年3月,通过使用随机分组的方式,分成对照组和观察组(重组人脑利钠肽联合益气复脉注射液),每组各46例。对两组患者的血气指标、心功能指标、NT-proBNP水平、临床治疗有效率、不良反应发生率。结果治疗前两组动脉血氧分压、动脉二氧化碳分压、心功能指标、NT-proBNP水平对比差异无统计学意义(P>0.05);治疗后,观察组动脉血氧分压指标高于对照组;观察组每搏输出量、心脏指数及左室射血分数指标高于对照组,左室舒张末期内径指标低于对照组;观察组NT-proBNP水平低于对照组;观察组临床治疗有效率高于对照组,不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论在心力衰竭疾病中使用重组人脑利钠肽联合益气复脉注射液治疗方法,患者血气指标、心功能指标改善效果好,NT-proBNP水平显著下降,临床症状改善效果好,有助于预防患者出现较多的不良反应,疾病临床治疗效果突出。
Objective To observe the application effect of recombinant human brain natriuretic peptide combined with Yiqi Fumai injection in the treatment of heart failure.Methods A total of 92 patients with heart failure were randomly divided into control group and observation group(recombinant human brain natriuretic peptide combined with Yiqi Fumai injection),with 46 patients in each group.The blood gas index,cardiac function index,NT-proBNP level,clinical treatment efficiency and incidence of adverse reactions of the two groups of patients.Results Before treatment,there were no significant differences in arterial partial pressure of oxygen,arterial partial pressure of carbon dioxide,cardiac function indexes and NT-proBNP levels between the two groups(P>0.05).After treatment,the observation group of arterial blood oxygen partial pressure index is higher than the control group and observation group each stroke volume,cardiac index and left ventricular ejection fraction index is higher than the control group,left ventricular end-diastolic diameter index is lower than the control group and observation group NT-proBNP level lower than the control group,the clinical efficient of the observation group is higher than the control group,incidence of adverse reactions observed group is lower than the control group,the difference was statistically significant(P<0.05).Conclusion The use of recombinant human brain natriuretic peptide combined with Yiqi Fumai injection in the treatment of heart failure disease,patients with blood gas indicators,heart function indicators improve the effect of good,NT-proBNP level significantly decreased,clinical symptoms improve the effect is good,help to prevent patients with more adverse reactions,the clinical treatment of the disease is outstanding.
作者
邱凯
汤期辉
陈新坡
QIU Kai;TANG Qihui;CHEN Xinpo(Sanming Hospital of Integrated Traditional Chinese and Western Medicine,Sanming 365000,China)
出处
《中国医药指南》
2022年第21期117-119,123,共4页
Guide of China Medicine
关键词
心力衰竭
重组人脑利钠肽
益气复脉注射液
心功能
不良反应
治疗效果
Heart failure
Recombinant human brain natriuretic peptide
Yiqi Fumai injection
Cardiac function
Adverse reactions
Therapeutic effect
