摘要
乳腺癌是女性发病率最高的恶性肿瘤之一,严重影响患者身心健康。即刻假体乳房再造术是乳腺癌术后修补乳房缺损的有效方法。包膜挛缩作为即刻假体乳房再造术后常见并发症之一,严重时可引起患者乳房疼痛及外形改变。但目前关于包膜挛缩的病因及发病机制仍不清楚,预防措施也存在局限性。包膜挛缩的病因具有多样性,与患者自身因素、手术切口位置、术后出血和血肿、植入物类型等均密切相关。因此,明确包膜挛缩的病因对疾病的预防尤为重要。此外,治疗时还应减少细菌污染、早期预防性抗炎、选择合适的植入物或通过脱细胞真皮基质辅助乳房再造,从而降低包膜挛缩的发生率。
Breast cancer is one of the most common malignant tumors in women,which severely affects the physical and mental health of the patients.Radical mastectomy combined with immediate breast reconstruction is an effective method to treat breast cancer and repair breast defects.Capsular contracture is one of the most common complications of immediate breast reconstruction and can cause breast pain and changes in appearance.However,the cause and mechanism are still unclear,and its preventions still have limitations.The etiology of capsular contracture is diverse,which is closely related to the patient′s own factors,surgical incision location,postoperative bleeding and hematoma,and implant type etc.Therefore,to clarify the etiology of capsular contracture is particularly important for the prevention.Besides,it is necessary to reduce bacterial contaminationimplement early preventive anti-inflammation and select appropriate implants,or realize breast reconstruction assisted by acellular dermal matrix,so as to reduce the incidence of capsular contracture.
作者
姚禹
穆大力
YAO Yu;MU Dali(Department Eight of Plastic Surgery,Plastic Surgery Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100144,China)
出处
《医学综述》
CAS
2022年第14期2855-2860,共6页
Medical Recapitulate
基金
中国医学科学院医学与健康科技创新工程项目(2020-I2M-C&T-B-081)。
关键词
即刻假体乳房再造术
包膜挛缩
预防措施
Immediate breast reconstruction
Capsular contracture
Preventive measure
