摘要
目的:探讨沙丁胺醇联合布地奈德雾化吸入对慢阻肺急性发作治疗价值体会。方法:将本院2018年1月至2020年12月收治的2018年1月至2020年12月患者作为此次研究对象,采用随机综合平衡法将研究对象分为对照组(n=33,单一使用沙丁胺醇雾化吸入)和试验组(n=33,沙丁胺醇联合布地奈德雾化吸入),比较两组治疗效果。结果:试验组的治疗有效率比对照组高(P<0.05),治疗前,两组肺功能指标及血气分析水平对比无明显区别(P>0.05);治疗后,试验组MVV、FVC和FEV_(1)%pred水平均高于对照组,试验组患者PaCO_(2)指标较低,且PaO_(2)指标较高,两组差异明显(P<0.05)。结论:沙丁胺醇联合布地奈德雾化吸入治疗慢阻肺急性发作效果显著,有效改善其动脉血气指标,促进肺功能康复。
Objective:To discuss the clinical value of salbutamol and budesonide aerosol inhalation in treating the acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:Patients treated from January 2018 to December 2020 in our hospital were selected as research subjects.According to comprehensive equilibrium method,patients were assigned to control group(n=33,salbutamol aerosol inhalation)and experimental group(n=33,salbutamol and budesonide aerosol inhalation).Treatment outcomes were probed.Results:The effective treatment rate in the experimental group was higher than control group(P<0.05);before treatment,lung function indicators and blood gas analysis index between groups were not significantly different(P>0.05);after treatment,MVV(maximum voluntary ventilation),FVC(forced vital capacity)and FEV_(1)%pred values in the experimental group were higher than control group;PaCO_(2)(partial pressure of carbon dioxide)values in the experimental group were lower than control group;PaO_(2)(partial pressure of oxygen)values in the experimental group were higher than control group(P<0.05).Conclusion:Salbutamol and budesonide aerosol inhalation can improve the arterial blood gas index and promote the lung function rehabilitation for acute exacerbation of chronic obstructive pulmonary disease patients.
作者
宁奕明
Ning Yiming(Wuchuan City Maternal and Child Health and Family Planning Service Center,Zhanjiang Guangdong 524500)
出处
《黑龙江医药》
CAS
2022年第4期832-835,共4页
Heilongjiang Medicine journal
关键词
沙丁胺醇
布地奈德
雾化吸入
慢阻肺急性发作
Salbutamol
Budesonide
Aerosol inhalation
Acute exacerbation of chronic obstructive pulmonary disease
