摘要
目的分析柴胡疏肝散加减在肝胃气滞型胃脘痛治疗中的临床效果。方法选择2018年1月—2021年6月邳州市中医院收治的60例肝胃气滞型胃脘痛患者为研究对象,依据随机数表法将其均分为两组,使用常规西药(雷贝拉唑钠肠溶胶囊+枸橼酸莫沙必利片)治疗30例纳入对照组,使用常规西药+柴胡疏肝散加减治疗的30例纳入观察组。对比两组治疗效果、中医症候积分及不良反应发生率。结果观察组治疗有效率(96.67%)高于对照组(73.33%),差异有统计学意义(χ^(2)=4.706,P<0.05)。治疗后,观察组主症、次症及总症候积分分别为(6.37±0.95)分、(4.25±0.50)分、(10.46±1.48)分,均低于对照组的(9.56±1.25)分、(6.78±0.79)分、(14.23±1.56)分,差异有统计学意义(t=11.129、14.822、9.603,P<0.05)。观察组不良反应发生率为10.00%,与对照组的16.67%对比,差异无统计学意义(χ^(2)=0.144,P>0.05)。结论在肝胃气滞型胃脘痛治疗中予以柴胡疏肝散加减治疗,效果显著,可促进患者病症改善,且不良反应少,安全性高。
Objective To analyze the clinical effect of modified Chaihu Shugan Powder in the treatment of epigastric pain of liver-stomach stagnation type.Methods A total of 60 patients with epigastric pain of liver-stomach qi stagna⁃tion type who were admitted to the Pizhou Hospital of Traditional Chinese Medicine from January 2018 to June 2021 were selected as the research objects.According to the random number table method,they were equally divided into two groups,30 cases were treated with conventional western medicine(rabeprazole sodium enteric-coated capsules+mosapride citrate tablets)and included in the control group,and 30 cases were treated with conventional western medicine+Chaihu Shugan 30 cases treated with the addition and subtraction of powder were included in the obser⁃vation group.The therapeutic effect,TCM symptom score and incidence of adverse reactions were compared between the two groups.Results The effective rate of treatment in the observation group(96.67%)was higher than that in the control group(73.33%),the difference was statistically significant(χ^(2)=4.706,P<0.05).After treatment,the scores of main symptoms,secondary symptoms and total symptoms in the observation group were(6.37±0.95)points,(4.25±0.50)points,(10.46±1.48)points,which were lower than those in the control group(9.56±1.25)points,(6.78±0.79)points,(14.23±1.56)points,the difference was statistically significant(t=11.129,14.822,9.603,P<0.05).The inci⁃dence of adverse reactions in the observation group was 10.00%,compared with 16.67%in the control group,the dif⁃ference was not statistically significant(χ^(2)=0.144,P>0.05).Conclusion In the treatment of epigastric pain of liver stomach qi stagnation type,the addition and subtraction of Chaihu Shugan Powder is effective,which can promote the improvement of patients'symptoms,and has few adverse reactions and high safety.
作者
俞正全
YU Zhengquan(Department of Spleen and Stomach Diseases,Pizhou Hospital of Traditional Chinese Medicine,Pizhou,Jiangsu Prov-ince,221300 China)
出处
《系统医学》
2022年第11期35-38,共4页
Systems Medicine
关键词
柴胡疏肝散
肝胃气滞
胃脘痛
症候积分
Chaihu Shugan Powder
Liver and Stomach Qi stagnation
Epigastric pain
Symptom score