摘要
目的 通过随机、多盲、意向性分析的临床对照研究,评估“化湿-补气-养阴”阶梯疗法治疗慢性疲劳综合征(Chronic Fatigue Syndrome,CFS)临床疗效及对生存质量的影响。方法 将符合纳入标准的100例CFS患者随机分为治疗组及对照组,各组50例。治疗组采用“化湿-补气-养阴”阶梯疗法进行干预治疗,对照组给予甘麦大枣汤进行干预治疗,2组均以3周为一个疗程,共治疗3个疗程。疗程结束后观察2组治疗前后患者临床症状、疲劳评定量表-14、健康状况调查问卷评分。结果 治疗组在用阶梯疗法治疗后,总体有效率98.0%;2组患者治疗结束后,患者躯体疲劳、脑力疲劳及总分相对比治疗前,差异均有统计学意义(P<0.05),治疗组在躯体疲劳、脑力疲劳及总分上,均优于对照组(P<0.05);2组患者的8个健康维度评分在治疗后,相比较治疗前,差异有统计学意义(P<0.05),3个疗程结束后,治疗组患者PF、RP、BP、GH、VT、SF、MH相比较对照组,差异均有统计学意义(P<0.05),但2组情感职能(RE)比较,差异无统计学意义(P> 0.05)。结论 “化湿-补气-养阴”阶梯疗法能明显改善患者疲劳症状,提高患者生存质量,从而提高临床疗效。
Objective By randam, multi-blind and intentional analysis of controlled clinical trial aiming to use “ removing dampnessreplenishing qi-nourishing yin” to treat chronic fatigue syndrome(CFS) of its clinical effects therapy and research the quality of life by three steps.Methods 100 cases of CFS patients meeting the inclusion criteria were randomly divided into treatment group and control group, with50 cases in each group. The treatment group was treated with step therapy of “removing dampness-replenishing qi-nourishing yin”, while the control group was treated with Ganmai Dazao decoction. Both groups received 3 weeks as a course of treatment, and a total of 3 courses of treatment. After treatment, clinical symptoms, fatigue rating Scale-14 and health status Questionnaire scores were observed in 2 groups before and after treatment.Results In the treatment group, the overall effective rate was 98%. After treatment, compared with before treatment,there were statistically significant differences in physical fatigue, mental fatigue and total score between the two groups(P< 0. 05), and the treatment group was significantly better than the control group in the comparison of physical fatigue, mental fatigue and total score(P<0. 05). After treatment, there were statistically significant differences in 8 health dimension scores between the two groups(P< 0. 05).After 3 courses, PF, RP, BP, GH, VT, SF and MH in the treatment group were compared with those in the control group(P< 0. 05).However, the emotional function(RE) of the two groups was compared. There was no significant difference(P> 0. 05).Conclusion The“removing dampness-replenishing qi-nourishing yin” step treatment can obviously improve patients’ fatigue symptoms, enhance patients’ life quality and advance clinical effects.
作者
武永利
马晓秀
杨磊
李春
WU Yongli;MA Xiaoxiu;YANG Lei;LI Chun(Department of Orthopedics of Traditional Chinese Medicine,General Hospital of Ningxia Medical University,Ningxia,Yinchuan 750004,China)
出处
《光明中医》
2022年第11期1894-1898,共5页
GUANGMING JOURNAL OF CHINESE MEDICINE
基金
宁夏回族自治区重点研发计划一般项目(No.2019BEG03070)
宁夏回族自治区第二批科技领军人才项目(No.KJT201610)
宁夏自然科学基金项目(No.2020A1082)。
关键词
化湿-补气-养阴阶梯疗法
慢性疲劳综合征
疲劳
dispelling dampness-replenishing qi-nourishing yin step therapy
chronic fatigue syndrome
fatigue
