摘要
目的:分析和血明目片联合激光光凝对视网膜静脉阻塞(RVO)继发黄斑水肿(ME)患者的影响。方法:选取2018年12月-2020年11月新余市人民医院收治的RVO继发ME的患者70例,双色球法随机分为对照组和试验组,均以雷珠单抗行基础治疗,试验组在此基础上加用和血明目片联合激光光凝治疗,组间对比疗效。结果:治疗前,两组视力指标[最佳矫正视力(BCVA)、眼压(IOP)、黄斑区网膜厚度(CMT)、黄斑阈值敏感度(MTS)]、眼底荧光血管造影术(FFA)结果(局部、囊样、弥漫渗漏及总渗漏)及两组治疗期间并发症发生率比较,差异均无统计学意义(P>0.05),治疗后,与对照组比较,试验组治疗总有效率较高,BCVA、MTS较高,CMT较低,FFA结果(局部、囊样、弥漫渗漏及总渗漏)发生率均较低,差异均有统计学意义(P<0.05)。结论:在对RVO继发ME的患者进行治疗时,增加和血明目片与激光光凝的联合治疗能显著改善患者的症状,提升视力并降低渗漏情况,且安全性好,具有推广价值。
Objective:To analyze the effect of Hexue Mingmu Tablets combined with laser photocoagulation on patients with macular edema (ME) secondary to retinal vein occlusion (RVO).Method:A total of 70 patients with ME secondary to RVO who were admitted to Xinyu People’s Hospital from December 2018 to November 2020 were selected and randomly divided into control group and experimental group by the double chromosphere method,all of them were treated with Lucentis as basic therapy,and 35 patients in the experimental group were treated with Hexue Mingmu Tablets combined with laser photocoagulation therapy,the curative effects were compared between groups.Result:Before treatment,there were no significant differences in visual acuity[best corrected visual acuity (BCVA),intraocular pressure (IOP),macular retinal thickness (CMT),macular threshold sensitivity (MTS)],fundus fluorescein angiography (FFA) results (local,cystic,diffuse leakage and total leakage) and the incidence of complications between the two groups during treatment (P>0.05).After treatment,compared with control group,the experimental group had higher total effective rate,higher BCVA and MTS,lower CMT and lower incidence of FFA results (local,cystoid,diffuse leakage and total leakage),with significant differences (P<0.05).Conclusion:In the treatment of patients with ME secondary to RVO,the combined treatment of Hexue Mingmu Tablets and laser photocoagulation therapy can significantly improve the symptoms of patients,improve vision and reduce leakage,and has good safety,which can be popularized value.
作者
毛蕾
MAO Lei(Xinyu People’s Hospital,Jiangxi Province,Xinyu 338000,China)
出处
《中国医学创新》
CAS
2022年第22期39-42,共4页
Medical Innovation of China
基金
新余市科学技术局项目(20203090857)。
关键词
和血明目片
激光光凝
视网膜静脉阻塞
黄斑水肿
视力
Hexue Mingmu Tablets
Laser photocoagulation
Retinal vein occlusion
Macular edema
Visual acuity
