摘要
The pathogenesis of can cer-related in som nia(CRI)mainly in eludes,first,the flow of cancerous toxin leading to the disorder of visceral qi;second,cancer-related radiotherapy and chemotherapy belonging to"exogenous pathogenic factors"to a certain extent,which can further aggravate visceral disorders.The therapeutic principle of Chinese medicine is to tranquilize the mind on the basis of regulating viscera,suppressing yang,and astringing yin.On this theoretical basis,Professor Zheng Yuling created a representative prescription of Zhenjing Anshen Granules(镇静安神颗粒)which can achieve the co-regulation of the heart,liver,and kidney,tranquilizing the mind and nourishing the blood.Clinically,the selection of prescriptions and medicines needs to be considered due to factors such as different treatment stages and differ-ences in patients'constitutions.
肿瘤相关性失眠(cancer related insomnia,CRI)的病机:一方面,癌毒流注,脏腑气机逆乱;另一方面,肿瘤相关放化疗一定程度上属于“外邪”侵犯,可以进一步加剧脏腑失调。中医治则是在调整脏腑、潜阳敛阴为基础上镇静安神。郑玉玲教授以此为理论依据,创立代表方药镇静安神颗粒,治疗CRI可达到心、肝、肾共调,重镇安神与养血安神共施之效果。临床上,因治疗阶段不同、患者体质差异等因素,选方遣药也需各有考量.
基金
supported by"Hundred-Thousand-Ten Thousand"Talents Project of Chinese Medicine Inheritance and Innovation(Qihuang Project)-Qihuang Scholars(284 Official Letter of People's Education of Chinese Medicine 2018)
Special Scientific Research Project of National Clinical Research Base of Traditional Chinese Medicine(2019JDZX001)
Special Scientific Research Project of National Clinical Research Base of Chinese Medicine(2019JDZX028)
Key Scientific Research Project of Henan Province Colleges and Universities(20A360005)
Henan Province Science and Technology Research and Social Development Project(202102310497).
