摘要
抗生素的不合理使用导致细菌耐药问题日趋严峻,给人类健康造成巨大威胁。学者们对抗生素抗性菌和抗生素抗性基因(antibiotic resistance genes,ARGs)在多种环境介质中的环境行为开展了大量研究。气溶胶作为ARGs的潜在储存库,是抗生素抗性基因在环境中的重要传播途径之一。目前缺乏对其来源、传播、人类接触和健康风险系统性的梳理。本文针对人类生活功能场所、养殖场、城市污水处理厂和医院等4类气溶胶研究的典型场所,重点综述了上述4类典型场所中气溶胶ARGs的来源、传播途径及对人体的暴露和对健康的危害,为气溶胶中ARGs的预防和控制提供参考。
Recently,drug resistance resulted from the extensive abuse and over-use of antibiotics has posed a great threat to human health.Scholars have conducted numerous studies on the impacts of antibiotic resistant bacteria and antibiotic resistance genes(ARGs)in different types of environments.Aerosol is not only a potential reservoir for ARGs,but also an important route for transmission of ARGs in the environment.However,a systematic summary of its sources,transmission,human exposure,and health risks is lacking.This review focused on four types of typical sites for aerosol research:human functional living places,farms,urban wastewater treatment plants,and hospitals.The sources,transmission routes,human exposure,and health risks of ARGs in the aerosol of these four typical sites were reviewed.This article also provides a reference for prevention and control of ARGs in aerosols.
作者
李中浤
薛媚
李顺江
杜彩丽
李晓光
LI Zhonghong;XUE Mei;LI Shunjiang;DU Caili;LI Xiaoguang(Institute of Water Ecology and Environment,Chinese Research Academy of Environmental Sciences,Beijing 100012,China;College of Animal Science and Food Engineering,Jinling Institute of Technology,Nanjing 210038,Jiangsu,China;Institute of Plant Nutrition,Resources and Environment,Beijing Academy of Agriculture and Forestry Sciences,Beijing 100091,China)
出处
《生物工程学报》
CAS
CSCD
北大核心
2022年第7期2423-2432,共10页
Chinese Journal of Biotechnology
基金
国家重点研发计划(2019YFC0409202)。
关键词
气溶胶
抗生素抗性基因
抗性细菌
人类生活功能场所
养殖场
城市污水处理厂
医院
aerosol
antibiotic resistance genes(ARGs)
antibiotic resistant bacteria(ARB)
human functional living place
farms
urban wastewater treatment plant
hospital
