摘要
目的探讨经皮肾镜手术在输尿管结石患者中的应用效果。方法选取2017年3月至2021年6月于江西省赣州市立医院收治的84例输尿管结石患者作为研究对象,按随机数字表法将其分为对照组(n=42)与观察组(n=42)。对照组患者行输尿管镜手术治疗,观察组患者行经皮肾镜手术治疗。比较两组患者的肾功能相关指标[肌酐(Cr)、肾小球滤过率(GFR)、尿素氮(BUN)]、视觉模拟评分(VAS)、临床指标及结石清除率、术后并发症情况。结果术前,两组患者的Cr、GFR、BUN水平比较,差异无统计学意义(P>0.05);术后1周,两组患者的Cr、BUN水平均低于术前、GFR高于术前,观察组患者的BUN水平低于对照组,差异有统计学意义(P<0.05)。术前,两组患者的VAS评分比较,差异无统计学意义(P>0.05);术后1周,两组患者的VAS评分均低于术前,且观察组患者的VAS评分低于对照组,差异有统计学意义(P<0.05)。观察组患者的术中失血量多于对照组,住院时间长于对照组,结石清除率高于对照组,差异有统计学意义(P<0.05);两组患者的手术时间比较,差异无统计学意义(P>0.05)。观察组患者的术后并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论经皮肾镜手术治疗输尿管结石患者具有并发症少、结石清除率高、肾功能改善等优势,但是存在大出血风险。
Objective To investigate application effect of percutaneous nephroscopy in patients with ureteral calculi.Methods A total of 84 patients with ureteral calculi treated in Ganzhou Municipal Hospital of Jiangxi Province from March 2017 to June 2021 were selected as the research objects.They were divided into the control group(n=42)and the observation group(n=42)according to random number table method.The control group was treated by ureteroscopy and the observation group was treated by percutaneous nephroscopy.The renal function related indexes[creatinine(Cr),glomerular filtration rate(GFR),blood urea nitrogen(BUN)],visual analogue scale(VAS),clinical indexes,stone clearance rate and postoperative complications were compared between the two groups.Results Before operation,there were no significant differences in Cr,GFR and BUN levels between the two groups(P>0.05).One week after operation,the levels of Cr and BUN in the two groups were lower than those before operation,the GFR in the two groups was higher than that before operation,and the BUN level in the observation group was lower than that in the control group,the differences were statistically significant(P<0.05).Before operation,there was no significant difference in VAS score between the two groups(P>0.05).One week after operation,the VAS scores of the two groups were lower than those before operation,and the VAS score of the observation group was lower than that of the control group,the difference was statistically significant(P<0.05).The intraoperative blood loss of the observation group was more than that of the control group,the hospital stay of the observation group was longer than that of the control group,and the stone clearance rate of the observation group was higher than that of the control group,the differences were statistically significant(P<0.05).There was no significant difference in operation time between the two groups(P>0.05).The total incidence of postoperative complications in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Percutaneous nephroscopy in the treatment of patients with ureteral calculi has the advantages of less complications,high stone clearance rate and improving renal function,but there is a risk of massive hemorrhage.
作者
刘仁富
黄绍明
熊川川
LIU Renfu;HUANG Shaoming;XIONG Chuanchuan(Department of Urology,Ganzhou Municipal Hospital,Jiangxi Province,Ganzhou,341000,China)
出处
《中国当代医药》
CAS
2022年第22期99-102,共4页
China Modern Medicine
基金
江西省赣州市指导性科技计划任务(GZ2018ZSF435)。
关键词
经皮肾镜手术
输尿管结石
肾功能
结石清除率
视觉模拟评分
Percutaneous nephroscopy
Ureteral calculi
Renal function
Stone clearance rate
Visual analogue scale
