摘要
目的:评价给予慢性心力衰竭伴低氧血症患者行呼吸湿化治疗仪后对血气分析指标及D-二聚体水平的影响。方法:选取2017年10月~2019年10月本院收治的300例慢性心力衰竭伴低氧血症患者作为研究对象,将其随机分为给予鼻导管高流量吸氧的对照组和给予呼吸湿化治疗仪的观察组,各150例。比较2组治疗后血气分析指标、治疗前后D-二聚体水平、临床治疗效果以及心功能改善情况。结果:观察组治疗后的PaO_(2)、SaO_(2)、PaO_(2)/FiO_(2)、pH明显高于对照组,而HCO_(3)、PaCO_(2)则低于对照组,P<0.05;观察组治疗后的D-二聚体水平明显低于对照组,P<0.005。治疗总有效率较对照组,观察组显著较高,组间差异显著,具有统计学价值(P<0.05)。BNP及NT-proBNP水平治疗前组间无显著差异,不具有统计学价值(P>0.05);BNP及NT-proBNP水平治疗后均降低,观察组低于对照组,差异显著,具有统计学价值(P<0.05)。结论:呼吸湿化治疗仪治疗慢性心力衰竭伴低氧血症患者,可明显改善患者的血气分析指标和D-二聚体水平,有效缓解疾病。
Objective:To evaluate the effect of respiratory humidification therapy on blood gas and D-dimer level in patients with chronic heart failure and hypoxemia.Methods:300 patients with chronic heart failure and hypoxemia who were admitted in our hospital from October 2017 to October 2019 were randomly divided into control group with high flow oxygen inhalation of nasal catheter and observation group with respiratory humidification therapy instrument,150 cases each.The indexes of blood gas analysis,D-dimer level before and after treatment,clinical effect and improvement of cardiac function were compared between the two groups.Results:After treatment,PaO_(2),SaO_(2),PaO_(2)/FiO_(2) and pH in the observation group were significantly higher than those in the control group,while HCO_(3) and PaCO_(2) in the observation group were lower than those in the control group,P<0.05;The level of D-dimer in the observation group after treatment was significantly lower than that in the control group(P<0.005).The total effective rate of the treatment group was significantly higher than that of the control group,and the difference between the two groups was statistically significant(P<0.05).There was no significant difference in BNP and NT-proBNP levels between the two groups before treatment(P>0.05);BNP and NT-proBNP levels decreased after treatment,the observation group was lower than the control group,the difference was significant,with statistical value(P<0.05).Conclusion:The respiratory humidification therapy instrument can obviously improve the blood gas analysis index and D-dimer level in patients with chronic heart failure with hypoxemia,and effectively alleviate the disease.
作者
程蕾
CHENG Lei(Department of Cardiology,Shenyang Red Cross Hospital,Liaoning Shenyang 110000)
出处
《中国医疗器械信息》
2022年第13期140-142,共3页
China Medical Device Information
关键词
低氧血症
呼吸湿化治疗仪
血气分析指标
hypoxemia
respiratory humidification apparatus
blood gas analysis index
