摘要
妊娠期糖尿病(GDM)是妊娠期最常见的代谢紊乱性疾病,严重影响胎儿的正常发育。妊娠期血糖控制情况不仅与早产、巨大儿、低血糖、新生儿呼吸窘迫综合征、电解质紊乱、心脏发育畸形和肠道菌群紊乱等近期不良结局有关,而且与持续的糖耐量受损、肥胖、代谢综合征、神经精神疾病及眼科疾病等远期结局相关。正确认识GDM对新生儿近期与远期造成的不良影响及其相关机制,及时采取相应的防治措施,可显著改善妊娠结局。本文将对此作一综述。
Gestational diabetes mellitus(GDM)is the most common metabolic disorder during pregnancy,which seriously affects the normal development of the fetus.Blood glucose control during pregnancy is associated not only with recent adverse outcomes such as preterm birth,macrosomia,hypoglycemia,neonatal respiratory distress syndrome,electrolyte disorders,heart malformations and intestinal disorders,but also with long-term results such as conti-nued impaired glucose tolerance,obesity,metabolic syndrome,mental illness and eye disease.Correct understanding of adverse effects of GDM on newborn infants in the short and long term and their related mechanisms as well as timely prevention and treatment measures can significantly improve the outcome of pregnancy.This paper will make a summary of these problems.
作者
韩炜
唐成和
Han Wei;Tang Chenghe(Department of Neonatology,the First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,China)
出处
《中华实用儿科临床杂志》
CAS
CSCD
北大核心
2022年第14期1117-1120,共4页
Chinese Journal of Applied Clinical Pediatrics
基金
河南省医学科技攻关计划项目(201602149)。
关键词
妊娠期糖尿病
胎儿
婴儿
新生
不良结局
早产
Gestational diabetes mellitus
Fetus
Infant,newborn
Adverse outcome
Preterm birth
