摘要
目的分析早期胃癌疾病特点,评价采用腹腔镜下远端胃癌根治术治疗的临床优势。方法80例早期胃癌患者,随机分为对照组和观察组,每组40例。对照组采用开腹胃癌根治术治疗,观察组采用腹腔镜下远端胃癌根治术治疗。比较两组患者术后并发症(感染、吻合口瘘、肠梗阻、胃瘫)发生情况以及相关临床指标[出血量、淋巴结清扫数目、术后肛门排气时间、住院时间、血清胃泌素-17(G-17)水平、血清糖类抗原199(CA199)水平]。结果观察组患者术后并发症发生率5.00%低于对照组的22.50%,差异具有统计学意义(P<0.05)。观察组患者出血量(161.50±20.50)ml、G-17(15.45±5.05)pmol/L、CA199(30.40±3.02)U/ml均低于对照组的(285.50±25.50)ml、(20.22±5.60)pmol/L、(35.30±3.30)U/ml,术后肛门排气时间(32.50±3.30)h、住院时间(8.50±0.50)d均短于对照组的(43.30±3.50)h、(11.20±1.20)d,差异均具有统计学意义(P<0.05)。两组患者淋巴结清扫数目比较,差异无统计学意义(P>0.05)。结论采用腹腔镜下远端胃癌根治术治疗早期胃癌效果显著,降低了患者术后并发症发生风险、血清因子水平,改善了手术相关指标。
Objective To analyze the characteristics of early gastric cancer and evaluate the clinical advantages of laparoscopic distal gastrectomy for gastric cancer.Methods A total of 80 patients with early gastric cancer were randomly divided into control group and observation group,with 40 cases in each group.The control group received open radical gastrectomy for gastric cancer,and the observation group received laparoscopic distal gastrectomy for gastric cancer.Both groups were compared in terms of postoperative complications(infection,anastomotic fistula,intestinal obstruction,gastroparesis)and related clinical indicators[blood loss,number of lymph node dissections,postoperative anal exhaust time,hospitalization time,serum gastrin-17(G-17)level,serum carbohydrate antigen 199(CA199)level].Results The postoperative complication rate 5.00%in the observation group was lower than 22.50%in the control group,and the difference was statistically significant(P<0.05).In the observation group,the blood loss(161.50±20.50)ml,G-17(15.45±5.05)pmol/L,CA199(30.40±3.02)U/ml were lower than(285.50±25.50)ml,(20.22±5.60)pmol/L,(35.30±3.30)U/ml in the control group;the postoperative anal exhaust time(32.50±3.30)h,hospitalization time(8.50±0.50)d were shorter than(43.30±3.50)h,(11.20±1.20)d in the control group;all the differences were statistically significant(P<0.05).There was no statistically significant difference in the number of lymph node dissections between the two groups(P>0.05).Conclusion Laparoscopic distal gastrectomy for gastric cancer has significant effect in the treatment of early gastric cancer,and can reduce the risk of postoperative complications,serum factor levels and improve the surgery-related indicators.
作者
徐亮
XU Liang(No.5 Department of Surgery,Fengcheng Central Hospital,Fengcheng 118100,China)
出处
《中国现代药物应用》
2022年第14期59-61,共3页
Chinese Journal of Modern Drug Application
关键词
腹腔镜下远端胃癌根治术
早期胃癌
围术期指标
并发症
Laparoscopic distal gastrectomy for gastric cancer
Early gastric cancer
Perioperative indicators
Complications
