摘要
目的探讨快充式经鼻湿化高流量通气(THRIVE)在肥胖患者行无痛胃镜检查中的应用效果。方法选取2019年1月至2021年1月漳州正兴医院收治的80例需行无痛胃镜检查的肥胖患者作为研究对象,采用抽签法将其分为快充组(n=40)和传统组(n=40),快充组静脉麻醉过程中采用THRIVE,传统组采用传统鼻导管吸氧,比较两组胃镜检查情况、生命体征变化、不良事件、不良反应发生情况。结果两组的麻醉苏醒时间、丙泊酚用量比较,差异无统计学意义(P>0.05),快充组的胃镜检查时间短于传统组,差异有统计学意义(P<0.05)。两组麻醉给药前、检查开始时、检查5 min时的平均动脉压(MAP)、心率(HR)比较,差异无统计学意义(P>0.05)。快充组胃镜检查结束时的MAP、HR低于传统组,且低于本组检查开始时,差异有统计学意义(P<0.05)。两组麻醉给药前的血氧饱和度(SpO_(2))比较,差异无统计学意义(P>0.05)。快充组胃镜检查开始时、胃镜检查进行5 min时、胃镜检查结束时SpO_(2)均高于传统组,差异有统计学意义(P<0.05)。快充组检查开始时与检查5 min时SpO_(2)水平比较,差异无统计学意义(P>0.05),但其余时间点两两比较,差异均有统计学意义(P<0.05)。快充组的不良事件总发生率低于传统组,差异有统计学意义(P<0.05)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论静脉麻醉过程中采用THRIVE能够缩短行无痛胃镜检查肥胖患者检查时间,维持生命体征稳定,减少不良事件发生,且具备安全性。
Objective To explore the application effect of transnasal humidified rapid-insufflation ventilatory exchange(THRIVE)on patients with obesity undergoing painless gastroscopy.Methods A total of 80 obese patients requiring painless gastroscopy in Zhangzhou Zhengxing Hospital between January 2019 and January 2021 were selected as the research subjects,and they were divided into rapid-insufflation group(n=40)and traditional group(n=40)by drawing lots.THRIVE was used during intravenous anesthesia in rapid-insufflation group and traditional nasal cannula oxygen inhalation was adopted in traditional group.The gastroscopy status,vital signs,adverse events and occurrence of adverse reactions were compared between the two groups.Results There were no statistical differences in the recovery time of anesthesia and the dosage of Propofol between the two groups(P>0.05),and the gastroscopy time in rapid-insufflation group was shorter than that in traditional group,and the difference was statistically significant(P<0.05).There were no statistical differences in mean arterial pressure(MAP)and heart rate(HR)before anesthesia,at the beginning of examination and during 5 min of examination between the two groups(P>0.05).The MAP and HR at the end of gastroscopy in rapid-insufflation group were lower than those in traditional group,and were lower than those at the beginning of examination,and the differences were statistically significant(P<0.05).There was no statistical significance in blood oxygen saturation(SpO_(2))between the two groups before anesthesia(P>0.05),and the SpO_(2) values in rapid-insufflation group at the beginning of gastroscopy,during 5 min of gastroscopy and at the end of gastroscopy were higher than those in traditional group,and the differences were statistically significant(P<0.05).There was no significant difference in SpO_(2) at the beginning of examination compared with that during 5 min of examination in rapid-insufflation group(P>0.05),but the difference was statistically significant at any two time points in rapid-insufflation group(P<0.05). The total incidence rate of adverse events in rapid-insufflation group was lower than that in traditional group, and the difference was statistically significant (P<0.05). There was no statistical significant differences in the total incidence rate of adverse reactions between the two groups (P>0.05). Conclusion The application of THRIVE during intravenous anesthesia can shorten the exa mination time, maintain the stability of vital signs and reduce the occurrence of adverse events of patients with obesity undergoing painless gastroscopy, with safety.
作者
胡兵
宋伟
田友芳
陈俊
HU Bing;SONG Wei;TIAN Youfang;CHEN Jun(The Second Department of Anesthesiology,Zhangzhou Zhengxing Hospital,Fujian Province,Zhangzhou363000,China)
出处
《中国当代医药》
CAS
2022年第23期122-125,共4页
China Modern Medicine
关键词
快充式经鼻湿化高流量通气
鼻导管吸氧
肥胖
无痛胃镜
Transnasal humidified rapid-insufflation ventilatory exchange
Nasal cannula oxygen inhalation
Obesity
Painless gastroscopy
