摘要
目的 分析儿童肝母细胞瘤(HB)CT征象与穿刺活检及手术病理诊断的一致性,并探讨CT诊断的临床价值&方法 选取2016年2月至2021年1月于徐州市儿童医院收治的82例疑似HB患儿为研究对象,对所有患儿均行多层螺旋CT和超声检查,同时经肝穿刺活检行病理组织学检查,分析两种检查方法 与病理诊断结果 的一致性,并比较HB患儿CT征象与穿刺活检诊断的一致性。结果 82例疑似H B患儿中有48例确诊为HB,包括上皮型22例和上皮间叶混合型26例;34例为非HB。CT诊断HB的灵敏度、准确度均高于超声诊断(P<0.05),且CT诊断HB与病理诊断的Kappa值为0.924,大于超声诊断与病理诊断的Kappa值0.704。48例HB患儿CT上出血征象的检出率低于病理组织活检结果 (P<0.05),其余CT征象检出率与病理组织活检结果 无明显差异(p>0.05)。结论 相比于超声检查,CT诊断儿童HB的灵敏度和准确率较高,且其CT征象与穿刺活检的病理组织检查结果 一致性较高。
Objective To analyze the consistency of CT signs and needle biopsy in the diagnosis of children hepatoblastoma(HB),and explore the clinical value of CT diagnosis.Methods A total of 82 children with suspected HB admitted to Xuzhou Children’s Hospital were enrolled as the research subjects between February 2016 and Janua ry 2021.All underwent multi-slice spiral CT(MSCT) and ultrasound examinations.At the same time,pathological examination was conducted by liver biopsy.The consistency between the two methods and pathological diagnosis was analyzed.The diagnosis consistency of CT signs and needle biopsy in HB children was compared.Results Of the 82 children with suspected HB,there were 48 cases confirmed with HB(22 cases with epithelial type and 26 cases with epithelial-mesenchymal type) and 34 cases without HB.The sensitivity and accuracy of CT in the diagnosis of HB were higher than those of ultrasound(P<0.05).The Kappa value between CT and pathological diagnosis was 0.924,greater than that between ultrasound and pathology diagnosis(0.704).In the 48 children with HB,detection rates of bleeding by CT was lower than these by pathological biopsy(P<0.05),but the difference in detection rates of the other signs between CT and pathological biopsy was not statistically significa nt(P>0.05).Conclusion Compa red with ultrasound examination,sensitivity and accuracy of CT are higher in the diagnosis of HB in children.The consistency between CT signs and pathological biopsy is high.
作者
马菲
刘畅畅
张欣贤
MA Fei;LIU Chang-chang;ZHANG Xin-xian(Department of medical imaging,Xuzhou Children's Hospital,Xuzhou 221000,Jiangsu Province,China)
出处
《中国CT和MRI杂志》
2022年第9期112-114,共3页
Chinese Journal of CT and MRI
