摘要
中医对疾病病因病机及易患因素的认识有其独到之处,在风险预后研究中具有独特优势。中医治未病理论历史悠久,首见于《黄帝内经》。后世医家将治未病理论补充完善,并应用于临床实践,取得了良好的效果。随着现代医学的发展,构建结合现代医学研究成果与中医特色的病证结合风险预测模型成为新趋势。将古今中西医学结合,构建病证结合模式下的风险预测模型,有助于临床早期筛查及干预疾病,并为中西医结合提供思路。冠心病是常见慢性病之一,经皮冠状动脉介入术(PCI)是治疗冠心病的重要方法。支架内再狭窄(ISR)是PCI术后常见的并发症,严重影响冠心病患者的治疗效果和预后。对于PCI术后ISR,尽管部分患者可再次通过病变靶血管的球囊扩张及支架植入术解决,但仍有相当多的患者拒绝接受再次PCI。建立冠心病PCI术后ISR病证结合风险预测模型可为临床PCI术后ISR风险预测提供有效工具,为ISR高危人群的早期筛查和干预提供具有中医特色的参考指标,指导临床有针对性地监测和治疗,对于预防和减少ISR具有一定的临床意义和参考价值。
Traditional Chinese medicine(TCM) has its unique understanding of the etiology, pathogenesis, and risk factors of di-seases, and is advantageous in the study of risk prognosis.First recorded in Huangdi′s Internal Classic, the TCM theory of treating di-sease before its onset has a long history.Supplemented and improved by the later generations of doctors, the TCM theory of treating di-sease before its onset has been applied to clinical practice and achieved good results.With the development of modern medicine, it has become a new trend to construct the risk prediction model integrating the research results of modern medicine with disease and syndrome combination of TCM characteristics.The construction of risk prediction model of disease and syndrome combination is conducive to early clinical screening and intervention, and provides ideas for the integration of TCM and western medicine.Coronary heart disease(CHD) is one of the common chronic diseases, and percutaneous coronary intervention(PCI) is an important therapeutic approach.In-stent restenosis(ISR) is a common complication after PCI, which seriously affects the outcome and prognosis of patients.Although some patients can be treated with balloon dilatation and endovascular stents, a significant number of patients still refuse secondary stenting intervention.The construction of risk prediction model of disease and syndrome combination for ISR after PCI can provide an effective tool for clinical risk prediction of ISR and indicators with TCM characteristics for early screening and intervention of people at a high risk of ISR, and guide clinical monitoring and intervention, which has certain clinical significance and reference value for the prevention and reduction of ISR.
作者
张瑾
姚睿祺
王子涵
陶诗怡
陈颖
黄力
ZHANG Jin;YAO Rui-qi;WANG Zi-han;TAO Shi-yi;CHEN Ying;HUANG Li(Bejing Universiy of Chinese Medicine,Bejing 100029,China;China-Japan Friendship Hospital,Bejing 100029,China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2022年第14期3718-3722,共5页
China Journal of Chinese Materia Medica
关键词
病证结合
预测模型
冠心病
经皮冠状动脉介入术
支架内再狭窄
disease and syndrome combination
prediction model
coronary heart disease
percutaneous coronary intervention
in-stent restenosis
