摘要
目的探讨麦默通微创旋切术治疗乳腺肿瘤对患者术后并发症发生率及视觉模拟评分法(VAS)评分的影响。方法收集2020年1月至2021年1月接收的乳腺肿瘤患者78例,按电脑数字随机表法分为对照组和观察组,每组39例。对照组予以传统肿物切除术治疗,观察组予以麦默通微创旋切术治疗,对比2组应激反应、术后并发症及VAS评分、血管内皮生长因子(VEGF)与微血管密度(MVD)。结果观察组手术时间、切口长度、切口愈合时间及住院时间短于对照组,术中出血量少于对照组(P<0.05);术后1 d时,观察组的皮质醇(Cor)、肾上腺素(E)及去甲肾上腺素(NE)水平低于对照组(P<0.05);观察组术后并发症发生率为7.69%;低于对照组的25.64%(P<0.05);术后1 d、3 d、5 d、7 d时,观察组的VAS评分低于对照组(P<0.05);术后7 d时,观察组VEGF水平低于对照组(P<0.05),MVD阳性率与对照组比较差异无统计学意义(P>0.05)。结论麦默通微创旋切术治疗乳腺肿瘤可达到良好的微创效果,有助于降低手术应激反应、减少术后并发症,并且可缓解术后疼痛,降低VEGF水平。
Objective To investigate the effects of Mammotome minimally invasive rotary varicotomy in treatment of benign breast masses on the incidence of postoperative complications and the visual analogue scale(VAS)score.Methods A total of 78 patients with breast cancer who were treated in our hospital from January 2020 to January 2021 were enrolled in the study,who were randomly divided into two groups,with 39 cases in each group.The patients in control group were treated by traditional tumor resection,however,those in observation group were treated by Mammotome minimally invasive rotary varicotomy.The stress response,postoperative complications,VAS score,vascular endothelial growth factor(VEGF)and microvessel density(MVD)were observed and compared between the two groups.Results The operation time,incision length,incision healing time,hospital stay and ntraoperative bleeding volume in observation group were significantly less than those in control group(P<0.05).And the levels of cortisol(Cor),epinephrine(E)and norepinephrine(NE)at 1d after operation in observation group were significantly lower than those in control group(P<0.05).Moreover the incidence of postoperative complications in observation group was 7.69%,which was significantly lower than that(25.64%)in control group(P<0.05).In addition the VAS scores at 1d,3d,5d,7d after operation as well as VEGF levels at 7d after operation in observation group were significantly lower than those in control group(P<0.05).However there was nosignificant difference in the positive rate of MVD between the two groups(P>0.05).Conclusion Mammotome minimally invasive rotary varicotomy in treatment of breast tumors can achieve better therapeutic effects,which is helpful for reducing the surgical stress response and the incidence of postoperative complications,and relieving postoperative pain and reducing VEGF levels.
作者
王六林
王园园
李珍
张晓雷
张保山
WANG Liulin;WANG Yuanyuan;LI Zhen(Department of Mammary Glands,Yellow River Sanmenxia Hospital,He’nan,Sanmenxia 472000,China)
出处
《河北医药》
CAS
2022年第16期2508-2510,共3页
Hebei Medical Journal
关键词
麦默通微创旋切术
乳腺肿瘤
微创
应激反应
并发症
术后疼痛
Mammotome minimally invasive atherectomy
breast tumor
minimally invasive
stress response
complications
postoperative pain
