摘要
目的:观察CT定位下经颅磁刺激对卒中后运动功能障碍患者的治疗效果。方法:150例缺血型脑卒中患者按入院时间分为观察组(n=75)和对照组(n=75),两组患者一般资料无显著性差异。观察组患者给予CT定位下经颅磁刺激治疗,对照组患者给予常规经颅磁刺激治疗。于治疗前和治疗8周后评估患者下肢肌力、上下肢运动能力评分、平衡能力、生活能力以及治疗有效性。结果:观察组患者治疗后下肢肌力、上下肢运动能力评分、平衡能力、生活能力显著高于对照组(P<0.05);观察组治疗有效率显著高于对照组(84.00%vs 68.00%,P<0.05)。结论:CT定位下经颅磁刺激治疗对卒中后运动功能障碍患者疗效显著,其具体机制有待于神经生物学基础研究进一步揭示。
Objective To observe the treatment efficacy of transcranial magnetic stimulation therapy under CT localization in patients with motor dysfunction after stroke.Methods A total of 150 patients with ischemic stroke were enrolled and divided into observation group(n=75)and control group(n=75)according to the time of admission,and there was no significant difference in the general data between two groups.Patients in observation group were given transcranial magnetic stimulation therapy under CT localization,and those in control group were treated by conventional transcranial magnetic stimulation therapy.The lower extremities muscle strength,upper and lower extremities motor ability,balance and living ability were assessed before and at 8 weeks after treatment.In addition,treatment response rate was also compared between two groups.Results After treatment,the assessment scale scores of lower extremities muscle strength,upper and lower extremity motor ability,balance,living ability in observation group were significantly higher than those in control group(P<0.05).The treatment response rate of observation group was also significantly higher than that of control group(84.00%vs 68.00%,P<0.05).Conclusion Transcranial magnetic stimulation therapy under CT localization is highly effective in patients with poststroke motor dysfunction,and the specific mechanism needs to be further revealed by basic neurobiological research.
作者
徐亚辉
张晓芸
张冉
王培福
XU Yahui;ZHANG Xiaoyun;ZHANG Ran;WANG Peifu(Department of Neurology,Aerospace Central Hospital,Beijing 100049,China)
出处
《中国医学物理学杂志》
CSCD
2022年第8期1015-1019,共5页
Chinese Journal of Medical Physics
基金
首都临床特色研究项目(Z181100001718095)。
关键词
脑卒中
CT定位
经颅磁刺激
运动障碍
stroke
CT localization
transcranial magnetic stimulation
motor dysfunction
