摘要
目的分析1990—2019年中国胰腺炎疾病负担的变化趋势,为胰腺炎的防治提供参考。方法利用2019全球疾病负担数据库(GBD 2019),分析发病率、死亡率、伤残调整寿命年(DALYs)、死亡损失寿命年(YLLs)、伤残损失寿命年(YLDs)及其年龄标化率和平均年度百分比变化率(AAPC),分析1990—2019年中国胰腺炎疾病负担变化情况,并与美国及全球数据进行比较。结果2019年中国胰腺炎年龄标化发病率为26.76/10万,年龄标化死亡率为0.59/10万,年龄标化DALY率为16.09/10万,年龄标化YLL率为14.61/10万,年龄标化YLD率为1.48/10万。与1990年相比,中国胰腺炎年龄标化发病率、年龄标化死亡率、年龄标化DALY率、年龄标化YLL率和年龄标化YLD率分别下降了28.94%、45.33%、49.12%、50.98%和18.49%。随着人群年龄增长,中国胰腺炎疾病负担大致呈上升趋势。中国胰腺炎疾病负担指标与美国、全球水平相比更低。中、美、全球饮酒所致的胰腺炎DALY均持续上升。结论1990—2019年中国胰腺炎疾病负担呈持续下降趋势,且低于美国和全球水平,但饮酒所致胰腺炎和老年人胰腺炎疾病负担却在升高,需要针对高危人群采取防治措施以减轻疾病负担。
Objective This study aimed to analyze the disease burden of pancreatitis in China from 1990 to 2019 and to provide references for the prevention and treatment of pancreatitis.Methods The data were obtained from the Global Burden of Disease Study 2019(GBD 2019).The incidence,mortality,disability-adjusted life years(DALYs),years of life lost(YLLs),years lived with disability(YLDs)and their corresponding age-standardized rate,and annual average percentage change(AAPC)were selected as the main indicators to compare the burden of pancreatitis in China,the United States and globally from 1990 to 2019.Results In 2019,the age-standardized incidence,mortality,DALY,YLL,and YLD rates in China were 26.76/100000,0.59/100000,16.09/100000,14.61/100000,and 1.48/100000,respectively,and decreased by 8.94%,45.33%,49.12%,50.98%,and 18.49%,respectively,compared with those in 1990.The burden of pancreatitis in China gradually increased with age,but was lower than that in the United States and globally.The DALY due to alcohol continually increased in China,the United States,and globally.Conclusion From 1990 to 2019,the burden of pancreatitis in China shows a decreasing trend and is lower than that in the United States and globally.However,the disease burden caused by alcohol and aging is increasing;therefore,effective measurements to alleviate the burden of pancreatitis in China are needed.
作者
蒋梦可
陆宗庆
周伍明
刘万军
杨旻
JIANG Mengke;LU Zongqing;ZHOU Wuming;LIU Wanjun;YANG Min(The Laboratory of Cardiopulmonary Resuscitation and Critical Care Medicine,The Second Afiliated Hospital of Anhui MedicalUniversity,Hejei 230601,P.R.China;The Second Department of Intensive Care Unit,The Second Afiliated Hospital of Anhui Medical University,Hefei 230601,P.R.China)
出处
《中国循证医学杂志》
CSCD
北大核心
2022年第8期869-875,共7页
Chinese Journal of Evidence-based Medicine
基金
国家自然科学基金项目(编号:82072134、81601661)。
关键词
胰腺炎
发病率
死亡率
疾病负担
Pancreatitis
Incidence
Mortality
Burden of disease
