摘要
目的探讨惊恐障碍的治疗方法。方法将60例惊恐障碍患者随机分为两组,各30例。对照组给予帕罗西汀治疗,研究组加用rTMS治疗。分别在治疗前及治疗后第1、2、4、6周末采用HAMA进行评定,采用TESS评定不良反应。结果随治疗时间的延长,两组HAMA评分均呈下降趋势,但研究组下降幅度优于对照组;研究组有效率为86.67%,高于对照组的63.33%(χ^(2)=4.36,P=0.037);两组不良反应发生率比较无统计学意义(χ^(2)=0.071,P>0.05)。结论帕罗西汀联合rTMS治疗惊恐障碍,能提高疗效,安全可靠。
Objective To explore the treatment of panic disorder.Methods Sixty cases of panic disorder were randomly divided into two groups,with 30 cases in each group.The control group was treated with paroxetine,while the study group was treated with repetitive transcranial magnetic stimulation(RTMS).HAMA was used to evaluate before treatment and at the end of the 1st,2nd,4th and 6th week after treatment,and the adverse reactions were evaluated by TESS.Results As the treatment continued,HAMA scores of both groups showed a downward trend,but the decrease of the study group was found greater than that of the control group.The effective rate of the study group was 86.67%,which was higher than 63.33%of the control group(χ^(2)=4.36,P=0.037).There was no significant difference in the incidence of adverse reactions between the two groups(χ^(2)=0.071,P>0.05).Conclusion The combination of paroxetine and repetitive transcranial magnetic stimulation is safe and reliable in treating panic disorder.
作者
朱伟
ZHU Wei(Linyi City Mental Health Center,Linyi 276005,China)
出处
《山东医学高等专科学校学报》
2022年第4期257-259,共3页
Journal of Shandong Medical College
关键词
重复经颅磁刺激
帕罗西汀
惊恐障碍
Repetitive transcranial magnetic stimulation
Paroxetine
Panic disorder
