摘要
目的 分析针灸结合黄芪桂枝五物汤对保守治疗肘管综合征患者白细胞介素-1(IL-1)、神经生长因子(NGF)和功能恢复的影响。方法 选取96例肘管综合征患者,随机分为观察组与对照组,各48例。2组入院后均给予保守治疗,在此基础上观察组给予针灸结合黄芪桂枝五物汤治疗,对照组仅给予针灸治疗。比较2组治疗后肘管综合征功能评分、血清IL-1、NGF水平、尺神经肌电功能指标、手捏力及上肢功能障碍测定量表(DASH)评分。结果 观察组治疗后肘管综合征功能评分优良率(89.59%,43/48)明显高于对照组(72.92%,35/48)(P<0.05);治疗后2组IL-1水平较治疗前明显降低,NGF水平均较治疗前明显升高,观察组对IL-1、NGF水平的改善明显优于对照组(P<0.05);治疗后2组尺神经传导速度、波幅,手捏力均较治疗前明显升高,潜伏期较治疗前明显缩短,观察组优于对照组(P<0.05);治疗后2组手DASH、VAS、PPI评分均较治疗前明显降低,观察组明显低于对照组(P<0.05)。结论 针灸结合黄芪桂枝五物汤可明显减轻肘管综合征患者周围神经组织炎症损伤,促进神经的修复再生,提高患者运动功能和生活能力。
Objective To analyze the effects of acupuncture combined with Huangqi Guizhi Wuwu Decoction on the levels of interleukin-1 (IL-1),nerve growth factors (NGF) and the functional recovery in patients with the cubital tunnel syndrome treated conservatively.Methods A total of 96 patients with the cubital tunnel syndrome were selected and randomly divided into an observation group and a control group,with 48 cases in each.Both groups were given a conservative treatment after admission.On this basis,the observation group was treated with acupuncture combined with Huangqi Guizhi Wuwu Decoction,while the control group was treated only with acupuncture.The functional scores of cubital tunnel syndrome,levels of serum IL-1 and NGF,ulnar nerve EMG function indexes,scores of hand pinch force and disabilities of the arm,shoulder and hand (DASH) were compared between the two groups after treatment.Results After treatment,the excellent and good rate of cubital tunnel syndrome function scores in the observation group (89.59%,43/48) was significantly higher than that in the control group (72.92%,35/48) (P<0.05).After treatment,the levels of IL-1 in the two groups were significantly lower than those before treatment,while the levels of NGF were significantly higher,and the improvement of IL-1 and NGF in the observation group was significantly better than that in the control group (P<0.05).After treatment,the ulnar nerve conduction velocity,amplitude and hand pinch force of the two groups were significantly higher than those before treatment,and the incubation period was significantly shorter,and the observation group was better than the control group (P<0.05).After treatment,the scores of hand-DASH,VAS and PPI in the two groups were significantly lower than those before treatment,and the scores in the observation group were significantly lower than those in the control group (P<0.05).Conclusion Acupuncture combined with Huangqi Guizhi Wuwu Decoction can significantly reduce the inflammatory injury of peripheral nerve tissues in patients with the cubital tunnel syndrome,promote the nerve repair and regeneration,and improve their motor function and living ability.
作者
代丽
余航
陈华
付桐瑞
王翠娟
DAI Li;YU Hang;CHEN Hua;FU Tongrui;WANG Cuijuan(The Seventh Department of Orthopedics,Cangzhou Hospital of Integrated Chinese and Western Medicine,Cangzhou 061000,China;The First Department ofHand Microsurgery,Cangzhou Hospital of Integrated Chinese and Western Medicine,Cangzhou 061000,China)
出处
《长春中医药大学学报》
2022年第9期1011-1014,共4页
Journal of Changchun University of Chinese Medicine
基金
2021年度河北省中医药管理局中医药类科技计划项目(2021352)。
关键词
针灸
黄芪桂枝五物汤
肘管综合征
IL-1
NGF
功能恢复
acupuncture
Huangqi Guizhi Wuwu Decoction
cubital tunnel syndrome
interleukin-1(IL-1)
nerve growth factor(NGF)
functional recovery
