摘要
目的 探讨参松养心胶囊联合胺碘酮在心律失常患者中的应用价值。方法 选择2019年9月—2021年9月山东省邹城市人民医院收治的心律失常患者74例,按随机数表法分为两组,各37例。对照组予以胺碘酮治疗,研究组给予胺碘酮+参松养心胶囊治疗,两组均持续治疗8周。对比分析两组血流动力学、心电图结果、心功能及不良反应。结果 治疗前,两组纤维蛋白原(FIB)、血浆比黏度(RPV)、红细胞沉降率(ESR)、血细胞比容(HCT)、心率(HR)、QT间期(QTc)、QT离散度(QTd)、左室射血分数(LVEF)、左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)相比,差异无统计学意义(P>0.05);治疗后,研究组FIB、RPV、ESR、HCT分别为(302.41±19.44)g/L、(1.12±0.15)mPa/s、(14.43±1.60)mm/h、(32.98±5.01)%,低于对照组的(324.38±25.96)g/L、(1.69±0.18)mPa/s、(19.24±1.87)mm/h、(43.67±5.20)%,差异有统计学意义(t=4.121、14.798、11.888、9.005,P<0.001)。治疗后,研究组HR、QTd、LVESD、LVEDD低于对照组,QTc、LVEF高于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率相当,差异无统计学意义(P>0.05)。结论 参松养心胶囊联合胺碘酮能够有效改善心律失常患者血流动力学及心电图相关指标,促进心功能恢复,安全可靠,临床应用价值高。
Objective To explore the application value of Shensong Yangxin capsule combined with amiodarone in patients with arrhythmia.Methods A total of 74 arrhythmia patients admitted to Zoucheng People’s Hospital of Shandong Province from September 2019 to September 2021 were selected and divided into two groups according to the random number table method,with 37 cases in each group.The control group was treated with amiodarone,and the study group was treated with amiodarone + Shensong Yangxin Capsules.Both groups were treated for 8 weeks.The hemodynamics,electrocardiogram results,cardiac function and adverse reactions were compared between the two groups.Results Before treatment,fibrinogen(FIB),plasma specific viscosity(RPV),erythrocyte sedimentation rate(ESR),hematocrit(HCT),heart rate(HR),QT interval(QTc),QT dispersion(QTd),left ventricular ejection fraction(LVEF),left ventricular end-systolic diameter(LVESD),and left ventricular end-diastolic diameter(LVEDD),the difference was not statistically significant(P>0.05);after treatment,the FIB,RPV,ESR,and HCT of the study group were(302.41±19.44) g/L,(1.12±0.15) mPa/s,(14.43±1.60) mm/h,and(32.98±5.01) % lower than those of the control group(324.38±25.96) g/L,(1.69±0.18) mPa/s,(19.24±1.87) mm/h and(43.67±5.20) %,the difference was statistically significant(t=4.121,14.798,11.888,9.005,P<0.001).After treatment,HR,QTd,LVESD and LVEDD in the study group were lower than those in the control group,while QTc and LVEF in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the two groups was similar,and the difference was not statistically significant(P>0.05).Conclusion Shensong Yangxin Capsule combined with amiodarone can effectively improve the hemodynamics and ECG-related indexes of patients with arrhythmia,and promote the recovery of cardiac function.It is safe and reliable,and has high clinical application value.
作者
刘敏
李成秋
LIU Min;LI Chengqiu(Department of Cardiovascular Medicine,Zoucheng People's Hospital of Shandong Province,Jining,Shandong Province,273500 China)
出处
《系统医学》
2022年第14期115-119,共5页
Systems Medicine
关键词
心律失常
胺碘酮
参松养心胶囊
血流动力学
心电图结果
Arrhythmia
Amiodarone
Shensong Yangxin capsules
Hemodynamics
Electrocardiogram results
