摘要
目的了解安徽省百日咳流行病学特征。方法通过中国疾病预防控制信息系统收集2005-2021年安徽省百日咳报告病例,描述性分析百日咳发病率和分布特征;采用时空扫描分析确定百日咳发病的聚集性区域。结果2005-2021年安徽省共报告百日咳1941例,年均报告率为0.19/10万,报告发病率在2016年的0.04/10万至2019年的0.52/10万之间;<1岁、1-4岁、5-9岁、≥10岁报告发病率分别为9.34/10万(1256例)、0.79/10万(414例)、0.35/10万(226例)、0.01/10万(45例);5-8月份报告病例占总病例数的51.11%。时空扫描分析发现百日咳发病共存在6个时空聚集区,覆盖10个地市的45个县区。结论安徽省百日咳发病率近年呈上升趋势,以小年龄为主,且存在时空聚集性。需加强百日咳监测,提高实验室诊断能力,完善百日咳免疫策略。
Objective To explore epidemiological characteristics of pertussis in Anhui province.Methods We obtained and analyzed pertussis reports during 2005-2021 in Anhui from the China Disease Prevention and Control Information System to estimate incidences and temporal and age distributions of pertussis.We used spatial-temporal scanning analysis to identify areas associated with clustering of pertussis incidence.Results A total of 1941 pertussis cases were reported during 2005-2021 in Anhui,for an average annual incidence of 0.19 per 100000 population.Annual incidences per 100000 ranged 0.04 in 2016 to 0.52 in 2019;and incidences among<1-,1-4-,5-9-,and≥10-year-olds were 9.34(1256 cases),0.79(414 cases),0.35(226 cases),and 0.01(45 cases),respectively;51.11%of all cases were reported between May and August.Spatial-temporal scanning analysis identified 6 pertussis incidence clustering areas covering 45 counties/districts of 10 prefectures.Conclusions The incidence of pertussis increased in recent years in Anhui,especially among young children,and showed spatial-temporal clustering.We should enhance pertussis surveillance and laboratory diagnosis and improve pertussis immunization strategies.
作者
李涛
王斌冰
玄坤
唐继海
Li Tao;Wang Binbing;Xuan Kun;Tang Jihai(Anhui Provincial Center for Disease Control and Prevention,Hefei 230601,Anhui,China)
出处
《中国疫苗和免疫》
CSCD
北大核心
2022年第4期412-416,共5页
Chinese Journal of Vaccines and Immunization
关键词
百日咳
流行病学特征
时空聚集性
Pertussis
Epidemiological characteristics
Spatial-temporal clustering
