摘要
目的探讨溶栓联合早期肢体功能锻炼对急性脑梗死患者神经功能康复的影响。方法选取2018-09—2020-09中国人民解放军南部战区总医院急诊科、脑血管科收治的急性脑梗死患者96例为研究对象,所有患者入院后均于4.5 h内进行溶栓治疗。按肢体功能锻炼的时间分为观察组和对照组,观察组54例患者在溶栓24 h内进行肢体功能锻炼,对照组42例患者在溶栓治疗24 h后再给予肢体康复训练,共治疗2周。分别于治疗前、治疗2周后及治疗3个月后评估患者的肢体运动功能康复及并发症发生情况。结果治疗前2组Barthel指数、Fugl-Meyer量表评分、患肢关节Ashworth评分、Rankin评分和NIHSS评分差异均无统计学意义(P>0.05)。治疗后2周及治疗后3个月,观察组Barthel指数评分均明显高于对照组(t=4.605、4.303,P<0.05),Fugl-Meyer评分均明显高于对照组(t=3.371、3.866,P<0.05),患肢关节Ashworth评分、Rankin评分和神经功能缺损评分均明显低于对照组(P<0.05)。观察组并发症发生率14.29%(7/42),明显低于对照组的3.70%(2/54)(χ^(2)=4.987,P=0.025)。结论对急性脑梗死患者开展溶栓联合早期肢体功能锻炼能够显著改善肢体运动功能,促进神经功能康复,安全性好。
Objective To investigate the effect of thrombolysis combined with early limb functional exer⁃cise on neurological rehabilitation in patients with acute cerebral infarction.Methods A total of 96 patients with acute cerebral infarction admitted to the Emergency Department and Cerebrovascular Department of Southern Theater General Hospital from September 2018 to September 2020 were selected as the study subjects.All patients re⁃ceived thrombolytic therapy within 4.5 hours after admission.According to the time of limb function exercise,the patients were divided into observation group and control group.In the observation group,54 patients were given limb function exercise within 24 h of thrombolytic therapy,and in the control group,they were given limb rehabili⁃tation training after 24 h of thrombolytic therapy for a total of 2 weeks.The recovery of limb motor function and complications were evaluated before treatment,2 weeks after treatment and 3 months after treatment.Results Be⁃fore treatment,there was no significant difference in Barthel index,Fugl-Meyer score,Ashworth score,Rankin score and neurological deficit score between the two groups(P>0.05).After 2 weeks and 3 months of treatment,Barthel Index and Fugl-Meyer score of the observation group were significantly higher than those of the control group Fugl-Meyer scores were significantly higher than those of the control group(P<0.05).At 2 weeks and 3 months after treatment,the Barthel index score of the observation group was significantly higher than that of the control group(t=4.605 and 4.303,P<0.05),and the Fugl-Meyer score was significantly higher than that of the controlgroup(t=3.371and3.866,P<0.05).The incidence of complications in the observation group was 14.29%(7/42)significantly lower than that in the control group(3.70%(2/54),χ^(2)=4.987,P=0.025).Conclusion For patients with acute cerebral infarction,early thrombolysis combined with early limb functional exercise can significantly im⁃prove the limb motor function,promote the recovery of neurological function,with good safety.
作者
李琴
曾凡杰
唐绍辉
唐柚青
罗高权
古菁
邢然然
姚惠东
LI Qin;ZENG Fanjie;TANG Shaohui;TANG Youqing;LUO Gaoquan;GU Jing;XING Ranran;YAO Huidong(Southern Theater General Hospital of the Chinese People’s Liberation Army,Guangzhou 510010,China)
出处
《中国实用神经疾病杂志》
2022年第7期798-802,共5页
Chinese Journal of Practical Nervous Diseases
关键词
急性脑梗死
溶栓
肢体功能锻炼
神经功能康复
早期
Acute cerebral infarction
Thrombolysis
Limb function exercise
Neurological rehabilitation
Early
