摘要
目的研究经尿道钬激光前列腺剜除术(holmium laser enucleation of the prostate,HoLEP)与等离子前列腺电切术(plasma ki⁃netic resection of prostate,PKRP)治疗良性前列腺增生(benign prostatic hyperplasia,BPH)的临床疗效及安全性。方法选取2018年10月—2019年10月包头医学院第二附属医院泌尿外科收治的良性前列腺增生患者98例为研究对象,以随机数表法分为HoLEP组(行HoLEP)和PKRP组(行PKRP),各49例,分别对比两组术前一般资料、围术期资料、并发症以及术后随访指标。结果术前两组一般资料差异无统计学意义(P>0.05);相比PKRP组,HoLEP组切除组织质量更多、术中出血量少、血红蛋白下降值低、导尿管留置及术后住院时间短,差异有统计学意义(P<0.05);HoLEP组术后PVR、前列腺尿道部压力改善较PKRP组更明显,差异有统计学意义(P<0.05);HoLEP组术后并发症发生率4.1%明低于PKRP组24.5%,差异有统计学意义(χ^(2)=8.333,P<0.05);术后随访,两组国际前列腺症状评分(IPSS)、生活质量评分(QoL)、国际勃起功能评分(IIEF-5)、最大尿流速(Qmax)差异无统计学意义(P>0.05)。结论HoLEP与PKRP在治疗BPH时均安全有效,但HoLEP更具优势,更有发展前景。
Objective To study the clinical efficacy and safety of transurethral holmium laser enucleation of the prostate(HoLEP)and plasma re⁃section of the prostate(PKRP)in the treatment of benign prostatic hyperplasia(BPH).Methods A total of 98 patients with benign prostatic hy⁃perplasia who were treated in the Department of Urology of the Second Affiliated Hospital of Baotou Medical College from October 2018 to Oc⁃tober 2019 were selected as the subjects objects,random numbers were divided into HoLEP group(used HoLEP)and PKRP group(used PKRP),with 49 cases in each group.The preoperative general data,perioperative data,complications and postoperative follow-up indexes were compared between the two groups.Results There was no statistically significant difference between the two general data groups(P>0.05);compared with the PKRP group,the HoLEP group had more resection tissue quality,less intraoperative blood loss,lower hemoglobin drop,urinary catheter indwelling and shorter postoperative hospital stay,the difference was statistically significant(P<0.05);the improvement in postoperative PVR and prostatic urethral pressure was more pronounced in the HoLEP group than in the PKRP group,the difference was sta⁃tistically significant(P<0.05);the incidence of postoperative complications was 4.1%,which was significantly lower than that in the PKRP group,24.5%,the difference was statistically significant(χ^(2)=8.333,P<0.05);during postoperative follow-up,there was no statistically signifi⁃cant difference in International Prostate Symptom Score(IPSS),Quality of Life(QoL),International Erectile Function Score(IIEF-5),and maximum urinary flow rate(Qmax)between the two groups(P>0.05).Conclusion Both HoLEP and PKRP are safe and effective in the treat⁃ment of BPH,but HoLEP has more advantages and more development prospects.
作者
王宇
高文礼
WANG Yu;GAO Wenli(Baotou Medical College,Baotou,Inner Mongolia Autonomous Region,014010 China;Department of Urology,Second Affiliated Hospi-tal of Baotou Medical College,Baotou,Inner Mongolia Autonomous Region,014010 China)
出处
《世界复合医学》
2022年第7期57-61,共5页
World Journal of Complex Medicine
关键词
良性前列腺增生
钬激光剜除术
等离子电切术
安全性
Benign prostatic hyperplasia
Holmium laser enucleation
Plasma electrosurgery
Safety
