摘要
目的分析缺血性小卒中与轻度认知功能障碍的关系。方法选取2019年1月至2021年1月在杭州市富阳区中医院神经内科住院就诊的100例缺血性小卒中被检者作为研究组,同时选取同期100例健康体检者作为对照组,对两组被检者进行认知功能评估,收集完整的临床资料,记录两组被检者的一般临床资料及蒙特利尔认知评估量表(MoCA)评分,同时进行统计学分析。结果两组被检者一般临床资料比较,差异无统计学意义(P>0.05);研究组患病一季度的MoCA评分高于患病一周,差异有统计学意义(P<0.05);研究组患病一年MoCA评分与患病一周比较,差异无统计学意义(P>0.05);研究组患病一年MoCA评分低于患病一季度评分,差异有统计学意义(P<0.05)。研究组患病一周的MoCA评分及患病一年的MoCA评分低于对照组,差异有统计学意义(P<0.05);研究组患病一季度MoCA评分与对照组比较,差异无统计学意义(P>0.05)。研究组患病一季度认知功能评定量表(LOTCA)评分高于患病一周,患病一年LOTCA评分低于一季度,差异有统计学意义(P<0.05)。研究组患病一年后LOTCA评分与一周比较,差异无统计学意义(P>0.05)。研究组患病一周、患病一季度及一年的LOTCA评分低于对照组,差异有统计学意义(P<0.05)。研究组患病一季度的简易精神状态检查量表(MMSE)评分高于患病一周,差异有统计学意义(P<0.05);研究组患病一年的MMSE评分与患病一周比较,差异无统计学意义(P>0.05);研究组患病一年的MMSE评分低于患病一季度评分,差异有统计学意义(P<0.05)。研究组患病一周、一季度及一年的MMSE评分低于对照组,差异有统计学意义(P<0.05)。结论通过对缺血性小卒中被检者进行MoCA量表评价,发现该类被检者在患病后存在广泛的轻度认知功能障碍,提示应高度重视缺血性小卒中病发后的轻度认知功能障碍,以便进行早期干预,降低进一步的危害。
Objective To analyze the correlation between transient ischemic attack and mild cognitive impairment.Methods A total of 100 patients with transient ischemic attack who were hospitalized in the Department of Neurology from January 2019 to January 2021 in Hangzhou Fuyang Hospital of Traditional Chinese Medicine were selected as the research group,and 100 healthy subjects during the same period were selected as the control group,the two groups were evaluated for cognitive function,the complete clinical data were collected,the general clinical data and Montreal cognitive assessment(MoCA)score of the subjects in the two groups were recorded,and statistical analysis was performed at the same time.Results There was no significant difference in the general clinical data between the two groups(P>0.05).The MoCA score of the study group in the first quarter was higher than that in the first week,and the difference was statistically significant(P<0.05).There was no significant difference in MoCA score between one year and one week in the study group(P>0.05).The MoCA score of the study group in one year was lower than that in the first quarter,and the difference was statistically significant(P<0.05).The MoCA scores of the study group for one week and one year were lower than those of the control group,and the differences were statistically significant(P<0.05).There was no significant difference in MoCA score between the study group and the control group in the first quarter(P>0.05).In the study group,the Loewenstein occupational therapy cognitive assessment(LOTCA)score in the first quarter was higher than that in the first week,and the LOTCA score in the first year was lower than that in the first quarter,the differences were statistically significant(P<0.05).There was no significant difference in LOTCA score between one year after illness and one week after illness in study group(P>0.05).The LOTCA scores of the study group for one week,one quarter and one year were lower than those of the control group,the differences were statistically significant(P<0.05).The mini-mental state examination (MMSE) score of the study group in the first quarter was higher than that in the first week, the difference was statistically significant (P<0.05). There was no significant difference in MMSE score between one year after illness and one week after illness in the study group (P>0.05). The MMSE score of the study group in one year was lower than that in the first quarter, and the difference was statistically significant (P<0.05). The MMSE scores of the study group for one week, one quarter and one year were lower than those of the control group, and the differences were statistically significant (P<0.05). Conclusion The MoCA scale was used to evaluate the subjects with transient ischemic attack, and it was found that these subjects had extensive mild cognitive impairment after the disease, it is suggested that attention should be paid to the mild cognitive impairment after transient ischemic attack, in order to carry out early intervention and reduce further harm.
作者
张军莉
郎霞萍
ZHANG Junli;LANG Xiaping(Department of Neurology,Hangzhou Fuyang Hospital of Traditional Chinese Medicine,Zhejiang Province,Hangzhou311400,China)
出处
《中国当代医药》
CAS
2022年第25期89-92,共4页
China Modern Medicine
基金
浙江省杭州市医药卫生科技项目(oo20190482)。
