摘要
目的研究在危重症肺部感染患者中应用床旁纤维支气管镜关系治疗的临床效果。方法选取2020年1月-2021年6月在汕头潮南民生医院收治的60例危重症肺部感染患者,将其按照数字随机表法予以分组,每组30例,对照组实施常规治疗,研究组在常规治疗基础上实施床旁纤维支气管镜灌洗治疗,对比分析两组临床效果。结果从血清细胞因子指标分析,治疗前组间对比无统计学差异(P>0.05),治疗后研究组C反应蛋白、白介素-6、肿瘤坏死因子-α均低于对照组(P<0.05);从肺部通气功能分析,治疗前组间对比无统计学差异(P>0.05),治疗后研究组动脉血氧分压、氧合指数均高于对照组,动脉血二氧化碳分压低于对照组(P<0.05);从肺功能指标分析,治疗前组间对比无统计学差异,治疗后研究组每分钟最大呼气量、第一秒最大呼气量、第一秒最大呼气量与用力肺活量比值均高于对照组(P<0.05)。从不良反应情况分析,组间对比无统计学差异(P>0.05)。结论对于危重症肺部感染患者来说,床旁纤维支气管镜灌洗治疗效果确切,可以使炎症感染减轻,同时对通气功能有改善作用,进而改善患者肺部功能,临床价值显著。
Objective To study the clinical effect of bedside fiberoptic bronchoscopy in critically ill patients with pulmonary infection.Methods From January 2020 to June 2021,60 critically ill patients with pulmonary infection were selected and divided into groups according to the numerical random table method,with 30 patients in each group.The control group received conventional treatment,and the research group received bedside fiberoptic bronchoscopy lavage on the basis of conventional treatment.The clinical effects of the two groups were compared and analyzed.Results From the analysis of serum cytokine indexes,there was no significant difference between the groups before treatment,and C-reactive protein,interleukin-6 and tumor necrosis factor in the study group after treatment-α All were lower than those in the control group (P<0.05);From the analysis of pulmonary ventilation function,there was no significant difference between the groups before treatment.After treatment,the arterial oxygen partial pressure and oxygenation index in the study group were higher than those in the control group,and the arterial carbon dioxide partial pressure was lower than that in the control group (P<0.05);From the analysis of pulmonary function indexes,there was no significant difference between the groups before treatment.After treatment,the maximum expiratory volume per minute,the maximum expiratory volume in the first second,and the ratio of the maximum expiratory volume in the first second to forced vital capacity in the study group were higher than those in the control group (P<0.05).From the analysis of adverse reactions,there was no significant difference between the groups (P>0.05).Conclusion For critically ill patients with pulmonary infection,bedside fiberoptic bronchoscope lavage has a definite effect,which can reduce inflammation and infection and improve ventilation function,showing significant clinical value.
作者
俞光胜
YU Guangsheng(Department of Respiratory and Critical Care Medicine,Shantou Chaonan Minsheng Hospital,Shantou,Guangdong,515144)
出处
《智慧健康》
2022年第20期79-82,共4页
Smart Healthcare
关键词
床旁纤维支气管镜灌洗
危重症
肺部感染
通气功能
血清细胞因子
不良反应
Bedside fiberoptic bronchoscopy lavage
Critically ill
Lung infection
Ventilation function
Serum cytokines
Adverse reactions
