摘要
目的分析老年人原发性高血压伴高尿酸血症临床治疗及效果。方法以北京市昌平区北七家社区卫生服务中心2019年1月-2020年12月收治的240例老年原发性高血压伴高尿酸血症患者为本次研究对象,所选研究对象以治疗方案差异分为厄贝沙坦组(120例,厄贝沙坦治疗)和氯沙坦组(120例,氯沙坦治疗),对比分析两组患者治疗前后的血压(收缩压:SBP,舒张压:DBP)、血尿酸水平、治疗有效率及不良反应发生率。结果①两组患者治疗前后的血压水平均无对比差异(P>0.05),但治疗后的氯沙坦组患者的血尿酸水平显著低于厄贝沙坦组患者(P<0.05);②厄贝沙坦组和氯沙坦组患者的治疗有效率分别为88.33%(106/120)、95.83%(115/120),氯沙坦组显著高于厄贝沙坦组(P<0.05);③厄贝沙坦组和氯沙坦组患者的不良反应发生率分别为13.33%(16/120)、5.83%(7/120),氯沙坦组显著低于厄贝沙坦组(P<0.05)。结论在老年人原发性高血压伴高尿酸血症患者的临床治疗中,以氯沙坦进行治疗,可有效起到降压、降脂及降低血尿酸水平的治疗效果,疗效显著,值得临床推广应用。
Objective To analyze the clinical treatment and effect of essential hypertension with hyperuricemia in the elderly.Methods Two hundred and forty elderly patients with essential hypertension and hyperuricemia admitted to our hospital from January 2019 to December 2020 were selected as the subjects of this study.The selected subjects were divided into irbesartan group(120 cases,irbesartan treatment)and losartan group(120 cases,losartan treatment).The blood pressure(systolic blood pressure:SBP,diastolic blood pressure:DBP),the level of blood uric acid,the effective rate of treatment and the incidence of adverse reactions were compared and analyzed between the two groups before and after treatment.Results①There was no difference in the blood pressure levels of the two groups before and after treatment(P>0.05),but the blood uric acid level of the losartan group after treatment was significantly lower than that of the irbesartan group(P<0.05).②The effective rates of treatment for patients in the irbesartan group and the losartan group were 88.33%(106/120)and 95.83%(115/120)respectively,and the losartan group was significantly higher than that of the irbesartan group(P<0.05).③The incidence of adverse reactions in the irbesartan group and the losartan group were 13.33%(16/120)and 5.83%(7/120),respectively,and the losartan group was significantly lower than Irbesartan group(P<0.05).Conclusion In the clinical treatment of elderly patients with essential hypertension and hyperuricemia,treatment with losartan can effectively reduce blood pressure,lipids and blood uric acid levels.The therapeutic effect is significant and it is worth while clinical promotion and application.
作者
李丽
LI Li(Department of General Practice,Beiqijia Community Health Service Center of Changping District,Beijing,102209)
出处
《智慧健康》
2022年第19期36-39,共4页
Smart Healthcare
