摘要
目的:观察血府逐瘀汤加减联合双侧去骨瓣减压开颅手术治疗重型对冲性脑挫裂伤的临床疗效。方法:选取重型对冲性脑挫裂伤患者70例,按随机数字表法分为观察组和对照组各35例。对照组在西医常规治疗的基础上给予双侧去骨瓣减压开颅术治疗,观察组在对照组的基础上联合血府逐瘀汤加减治疗。2组疗程均为14 d。观察2组治疗前及治疗1、14 d时颅内压情况,治疗前及治疗14 d时格拉斯哥昏迷指数(GCS)评分变化,并统计2组治疗期间并发症发生情况。结果:治疗前,2组颅内压水平比较,差异无统计学意义(P>0.05);治疗1、14 d后,2组颅内压均较治疗前明显降低(P<0.05),且观察组在相同治疗时间点的颅内压均低于对照组(P<0.05)。治疗前,2组GCS评分比较,差异无统计学意义(P>0.05);治疗14 d后,2组GCS评分均较治疗前升高(P<0.05),且观察组GCS评分高于对照组(P<0.05)。观察组并发症发生率为8.57%,对照组为28.57%,2组比较,差异有统计学意义(P<0.05)。结论:血府逐瘀汤加减联合双侧去骨瓣减压开颅术治疗重型对冲性脑挫裂伤,可有效降低患者颅内压,改善其昏迷症状,减少术后并发症。
Objective:To observe the clinical effect of Modified Xuefu Zhuyu Tang Combined with Bilateral Decompressive Craniotomy for severe contrecoup contusion and laceration of brain.Methods:A total of 70 cases of patients with severe contrecoup contusion and laceration of brain were selected and divided into the observation group and the control group according to the random number table method,with 35 cases in each group.Based on routine western medicine treatment,the control group was treated with bilateral decompressive craniotomy,and the observation group was additionally treated with modified Xuefu Zhuyu tang based on the treatment of the control group.Both groups were treated for 14 days.The intracranial pressure before treatment and 1 and 14 days after treatment,and the changes in Glasgow Coma index(GCS) scores before treatment and 14 days after treatment in the two groups were observed.Incidence of complications in the two groups during treatment was counted.Results:Before treatment,there was no significant difference being found in the comparison of the levels of intracranial pressure between the two groups(P>0.05).After 1 and 14 days of treatment,intracranial pressure in the two groups was significantly decreased when compared with that before treatment(P<0.05),and intracranial pressure in the observation group was lower than that in the control group at the same treatment time points(P<0.05).Before treatment,there was no significant difference being found in the comparison of GCS scores between the two groups(P>0.05).After 14 days of treatment,GCS scores in the two groups were increased when compared with those before treatment(P<0.05),and GCS score in the observation group was higher than that in the control group(P<0.05).The incidence of complications was 8.57% in the observation group and 28.57% in the control group,the difference being significant(P<0.05).Conclusion:Modified Xuefu Zhuyu Tang Combined with Bilateral Decompressive Craniotomy for severe contrecoup contusion and laceration of brain can effectively reduce intracranial pressure and the incidence of postoperative complications,and improve coma degree.
作者
毛伟龙
姜一鸣
范小明
MAO Weilong;JIANG Yiming;FAN Xiaoming
出处
《新中医》
CAS
2022年第16期48-51,共4页
New Chinese Medicine
关键词
重型对冲性脑挫裂伤
血府逐瘀汤
双侧去骨瓣减压开颅术
格拉斯哥昏迷指数
Severe contrecoup contusion and laceration of brain
Xuefu Zhuyu tang
Bilateral decompressive craniotomy
Glasgow Coma index
