摘要
急性缺血性脑卒中(AIS)是一种由于脑动脉狭窄或血栓阻塞导致脑血供不足而引起的脑组织缺血性损伤的疾病。心源性脑卒中占所有AIS的25%~30%,而心房颤动相关脑卒中占所有心源性脑卒中的79%以上,心房颤动是最重要的危险因素。心房颤动相关脑卒中症状更严重,致残率、致死率更高,更易复发,病死率是非心房颤动相关脑卒中的2倍。目前,心房颤动相关AIS的治疗方法有静脉溶栓、血管内机械取栓、桥接治疗及单纯抗凝,等。文中对上述治疗方法的研究进展进行综述。
Acute ischemic stroke(AIS) is a disease of brain tissue damage caused by cerebral artery stenosis or thrombus obstruction that causes insufficient blood supply to the brain.Cardiogenic stroke accounts for 25%-30% of all AIS,and atrial fibrillation-related stroke accounts for more than 79% of all cardiac strokes and is the most important risk factor.Atrial fibrillation-associated stroke has more severe symptoms,higher rates of disability and mortality,and is more likely to relapse.The mortality rate is twice that of non-atrial fibrillation-associated stroke.The current treatment methods for AIS associated with atrial fibrillation include intravenous thrombolysis,mechanical thrombolysis,bridging therapy,and simple anticoagulation.The research progress of the above treatment methods were discussed.
作者
于妍
王丽华
孔晓彤
白雪
苏万玲
刘佩芳
YU Yan;WANG Li-hua;KONG Xiao-tong;BAI Xue;SU Wan-ling;LIU Pei-fang(Department of Neurology,the Second Affiliated Hospital of Harbin Medical University,Haerbin 150081,China)
出处
《中国临床神经科学》
2022年第4期474-477,共4页
Chinese Journal of Clinical Neurosciences
基金
哈尔滨医科大学附属第二医院中青年创新科学研究基金(编号:KYCX2019-12)。
关键词
急性缺血性脑卒中
心房颤动
静脉溶栓
血管内机械取栓
acute ischemic stroke
atrial fibrillation
intravenous thrombolysis
endovascular mechanical embolectomy
