摘要
目的:评估儿童腹股沟异位肾上腺皮质组织(EACT),并分析其发病率与诊断、年龄之间的关系。方法:回顾性分析2015年1月至2019年12月广州市妇女儿童医疗中心收治的1059例睾丸固定术与腹股沟其他手术患者的临床资料,其中34例异位肾上腺患者,应用SPSS 22.0统计学软件进行分析并综合文献回顾。结果:670例行睾丸固定术,389例行鞘膜积液高位结扎术。共发现34例(2.83%)异位肾上腺患者,主要集中在2岁以下(20例,58.9%);其中睾丸固定术中发现率为4.18%,鞘膜积液高位结扎术中发现率为0.514%(P<0.05)。将异位肾上腺患者按照手术方式不同分为睾丸固定术组与非睾丸固定术组,非睾丸固定术组中位数年龄为24个月,范围为11~120个月;睾丸固定术组中位数年龄为19个月,范围为10~108个月,两组年龄比较,差异无统计学意义(P=0.340)。670例睾丸固定术中,<7岁手术组26例(4.27%),7~16岁手术组2例(3.28%),两者比较,差异无统计学意义(P=0.522)。结论:异位肾上腺组织可能与性腺下降的机制有关,而与年龄没有关系,临床上不建议手术探查,但发现则应完整手术切除。
Objective:To elucidate the inguinal ectopic adrenal cortical tissue(EACT)in children,and its incidence in relation to how it was diagnosed and the patient age.Methods:Retrospectively analyzed were the clinical data from 1059 patients who underwent orchiopexy or other inguinal surgeries in Guangzhou Women and Childrens Medical Center between January 2015 and December 2019,including 34 patients with EACT.SPSS 22.0 Statistical Software was used for data processing.A review of literature was performed.Results:A total of 670 children underwent orchiopexy and 389 others underwent high ligation of the hydrocele.EACT was found incidentally in 34 patients(2.83%),most of whom aged below 2 years(n=20,58.9%).The diagnostic yield of EACT was 4.18%during orchiopexy vs 0.514%during high ligation of the hydrocele(P<0.05).The patients with EACT were divided into the orchiopexy group and non⁃orchiopexy group according to the surgery they underwent.The median age in the non⁃orchiopexy group was 24 months(11⁃120 months)vs 19 months(10⁃108 months)in the orchiopexy group,with no significant difference in age between groups(P=0.340).Among 670 children who underwent orchiopexy,there were 26 EACT patients(4.27%)aged below 7 years,and 2(3.28%)aged 7⁃16 years old,with no significant difference in age between the two subgroups(P=0.522).Conclusion:Development of EACT may be mechanistically related to descent of the gonad but not to age.In clinical practice,surgical exploration is not recommendable but that complete surgical resection should be performed once EACT is found.
作者
张正涛
高晓峰
刘国昌
李仕坤
伏雯
Zhang Zhengtao;Gao Xiaofeng;Liu Guochang;Li Shikun;Fu Wen(Guangzhou Women and Children's Medical Center,Guangzhou Medical University,Guangzhou 510623,China;The Third Affilicated Hospital of Guangzhou Medical University,Guangzhou 510140,China)
出处
《广州医科大学学报》
2022年第4期61-64,94,共5页
Academic Journal of Guangzhou Medical University
关键词
异位肾上腺
睾丸下降不全
鞘膜积液
性腺下降
Ectopic adrenal cortical tissue
Incomplete descent of the testes
Hydrocele
Gonadal descent