摘要
目的探讨补肾活血方与枸橼酸氯米芬联合对排卵障碍性不孕症进行治疗的临床效果。方法基于特定时间(2020年1月—2021年12月)及固定范围内(本院妇科),选取排卵障碍性不孕症患者60例,将其分为实验组和对照组(随机数字表法,每组均为30例),对照组单纯给予枸橼酸氯米芬治疗,实验组在此基础上加用中药补肾活血方治疗,对比两组临床疗效,评定两组6个月内妊娠情况。结果实验组治疗总有效率(96.67%)较对照组(73.33%)高,差异有统计学意义(P<0.05)。实验组治疗后HCG注射日子宫内膜厚度较对照组高(P<0.05)。实验组治疗6个月时的窦卵泡数较对照组少(P<0.05),卵巢体积较对照组小(P<0.05)。实验组治疗6个月时的妊娠率(50.00%)较对照组(33.33%)高,但组间比较差异不明显(P>0.05)。结论针对排卵障碍性不孕症患者,采用补肾活血方与枸橼酸氯米芬相联合的方案进行治疗,能恢复卵巢功能,增加子宫内膜厚度,提高妊娠率,应用价值高。
Objective To explore the clinical effect of Bushen Huoxue Prescription combined with clomiphene citrate on the treatment of anovulatory infertility.Methods Sixty patients with anovulatory infertility admitted to the Department of Gynecology of Nanjing Gaochun Traditional Chinese Medicine Hospital from January 2020 to December 2021 were selected and divided into two groups by the random number table method,with 30 patients in each group.Group A was treated with clomiphene citrate,and group B was additionally treated with Bushen Huoxue Prescription based on group A.The clinical efficacy of the two groups was compared,and the pregnancy status of the two groups within 6 months was evaluated.Results The total effective rate of group B(96.67%)was higher than group A(73.33%)(P<0.05).The intrauterine thickness of group B was higher than that of group A on the day of human chorionic gonadotropin(HCG)injection after treatment(P<0.05).After 6 months of treatment,the number of sinus follicles in group B was less than that in group A(P<0.05),and the ovarian volume was smaller than that in group A(P<0.05).The pregnancy rate in group B(50.00%)was higher than in group A(33.33%)at 6 months after treatment,but there was no significant difference between groups(P>0.05).Conclusion The combination of Bushen Huoxue Prescription and clomiphene citrate has a good effect on patients with anovulation infertility,which can restore ovarian function,increase endometrial thickness,and improve pregnancy rate,thus having a high application value.
作者
诸丽萍
ZHU Liping(Department of Gynecology,Nanjing Gaochun Traditional Chinese Medicine Hospital,Nanjing 211300,Jiangsu,China)
出处
《基层中医药》
2022年第7期30-35,共6页
Basic Traditional Chinese Medicine
关键词
排卵障碍性不孕症
补肾活血方
枸橼酸氯米芬
anovulation infertility
Bushen Huoxue Prescription
clomiphene citrate
