摘要
目的了解1990—2019年浙江省心血管疾病(CVD)负担变化趋势,为全省CVD防控工作提供依据。方法通过2019年全球疾病负担研究(GBD 2019)数据库,收集1990—2019年浙江省CVD导致的伤残损失健康寿命年(YLD)、早死损失寿命年(YLL)和伤残调整寿命年(DALY)资料,采用YLD率、YLL率和DALY率评价CVD疾病负担;计算年度变化百分比(APC)分析CVD疾病负担变化趋势,并与全国及全球不同社会人口学指数(SDI)地区比较。结果1990—2019年浙江省CVD导致的YLL率(APC=-0.50%,F=22.366,P<0.001)和DALY率(APC=-0.20%,F=5.212,P=0.030)呈下降趋势,YLD率呈上升趋势(APC=1.92%,F=1117.891,P<0.001)。女性CVD导致的YLL率(APC=-1.09%,F=56.871,P<0.001)、YLD率(APC=1.92%,F=922.541,P<0.001)和DALY率(APC=-0.60%,F=28.974,P<0.001)变化趋势与全人群一致;男性仅YLD率变化显著,呈上升趋势(APC=1.82%,F=1238.423,P<0.001)。各年龄组YLL率和DALY率均呈下降趋势,其中50~<70岁人群下降最明显(APC=-4.40%,F=1443.608,P<0.001;APC=-3.82%,F=1519.452,P<0.001)。各类型心血管病中脑血管病负担最重,标化DALY率为1359.7/10万,风湿性心脏病导致的标化DALY率下降最明显。浙江省CVD疾病负担低于全国及全球多数地区,变化趋势与全国及全球各类SDI地区一致。结论1990—2019年浙江省CVD疾病负担整体呈下降趋势,与全国及全球各类SDI地区一致;女性、50~<70岁人群、风湿性心脏病的疾病负担下降较为明显。
Objective To investigate the changing trends in the burden of cardiovascular diseases(CVD)in Zhejiang Province from 1990 to 2019,so as to provide insights into CVD control in the province.Methods Based on the data of the Global Burden of Disease Study(GBD)2019(GBD 2019),the years lived with disability(YLD),years of life lost(YLL),disability-adjusted life years(DALY),YLD rate,YLL rate and DALY rate due to CVD were estimated to assess the burden of CVD in Zhejiang Province from 1990 to 2019.The changing trends in the burden of CVD were using annual percent change(APC)in Zhejiang Province from 1990 to 2019,and compared to China and global regions with different socio-demographic indexes(SDI).Results The YLL rate(APC=-0.50%,F=22.366,P<0.001)and DALY rate due to CVD(APC=-0.20%,F=5.212,P=0.030)appeared a tendency towards a decline in Zhejiang Province from 1990to 2019,while the YLD rate showed a tendency towards a rise(APC=1.92%,F=1117.891,P<0.001).The YLL rate(APC=-1.09%,F=56.871,P<0.001),YLD rate(APC=1.92%,F=922.541,P<0.001)and DALY rate(APC=-0.60%,F=28.974,P<0.001)appeared the same tendency among women relative to among the whole populations,while only the YLD rate showed a clear-cut change among men,appearing a tendency towards a rise(APC=1.82%,F=1238.423,P<0.001).Both the YLL rate and DALY rate appeared a tendency towards a decline among subjects at all age groups,with the most significant reduction among subjects at ages of 50 to 69 years(YLL rate:APC=-4.40%,F=1443.608,P<0.001;DALY rate:APC=-3.82%,F=1519.452,P<0.001).Among all types of CVD,the highest burden was measured in cerebrovascular diseases,with a standardized DALY rate of 1359.7/10~5,and the most remarkable reduction in the standardized DALY rate was seen in rheumatic heart diseases.The burden of CVD in Zhejiang Province was lower than that in China and the majority of the world,with consistent changing trends with that in China and global regions with different SDI.Conclusions The overall burden of CVD appeared a tendency towards a decline in Zhejiang Province from 1990 to 2019,which was in agreement with that in China and global regions with different SDI.A remarkable reduction in the burden of CVD was seen among women,residents at ages of 50 to 69 years and cases with rheumatic heart diseases.
作者
林永兴
刘足云
李娜
于村
LIN Yongxing;LIU Zuyun;LI Na;YU Cun(Department of Intergrated Support,Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou,Zhejiang 310051,China;Zhejiang University,Hangzhou,Zhejiang 310058,China;Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou,Zhejiang 310051,China)
出处
《预防医学》
2022年第10期1020-1025,共6页
CHINA PREVENTIVE MEDICINE JOURNAL
