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甲状腺功能五项指标联合检测法对甲状腺功能评估意义探讨 被引量:6

Discussion on the Significance of the Combined Detection Method of 5 Indexes of Thyroid Function in the Evaluation of Thyroid Function
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摘要 目的探讨临床评估甲状腺功能采用甲状腺功能5项指标联合检测的应用价值。方法本研究选择2020年1月—2021年5月新疆维吾尔自治区乌鲁木齐市中医医院健康体检者30名(对照组)、甲亢患者30例(观察A组)、甲减患者30例(观察B组)作为研究对象,对各组间甲功5项水平、诊断阳性率进行对比。结果观察A组T_(3)(4.73±0.58)nmol/L、FT_(3)(12.73±1.49)pmol/L、T_(4)(230.72±11.73)nmol/L、FT_(4)(35.14±3.77)pmol/L高于对照组、观察B组,且对照组T_(3)(1.86±0.24)nmol/L、FT_(3)(3.57±0.68)pmol/L、T_(4)(99.28±10.32)nmol/L、FT_(4)(13.33±1.28)pmol/L高于观察B组,差异有统计学意义(P<0.05);观察A组TSH(0.20±0.03)mIU/L低于对照组、观察B组,且对照组TSH(2.75±0.24)mIU/L低于观察B组,差异有统计学意义(P<0.05)。观察A组及观察B组的T_(3)、FT_(3)、T_(4)、FT_(4)、TSH诊断阳性率均高于对照组,差异有统计学意义(P<0.05),但观察A组上述指标检测诊断阳性率与观察B组对比,差异无统计学意义(P>0.05)。结论甲功5项水平进行联合检测的指标用于评估甲状腺功能效果显著,对临床甲状腺疾病的鉴别、诊断具有重要的指导意义。 Objective To explore the application value of the combined detection of 5 thyroid function indexes in clinical assessment of thyroid function.Methods In this study,30 healthy people(control group),30 patients with hyperthyroidism(observation group A),and 30 patients with hypothyroidism(observation group B)were selected from January 2020 to May 2021 in Urumqi Traditional Chinese Medicine Hospital,Xinjiang Uygur Autonomous Region,as research target.The levels of 5 items of thyroid function and the positive rate of diagnosis were compared among the groups.Results In group A,T_(3)(4.73±0.58)nmol/L,FT_(3)(12.73±1.49)pmol/L,T_(4)(230.72±11.73)nmol/L,and FT_(4)(35.14±3.77)pmol/L were higher than those in the control group,observation group B,and the control group T_(3)(1.86±0.24)nmol/L,FT_(3)(3.57±0.68)pmol/L,T_(4)(99.28±10.32)nmol/L,FT_(4)(13.33±1.28)pmol/L higher than the observation group B,the difference was statistically significant(P<0.05).The TSH(0.20±0.03)mIU/L in the observation group was lower than that in the control group and the observation group B,and the TSH in the control group(2.75±0.24)mIU/L was lower than that in the observation group B,the difference was statistically significant(P<0.05).The positive rates of T_(3),FT_(3),T_(4),FT_(4),and TSH in observation group A and observation group B were higher than those in the control group,and the difference was statistically significant(P<0.05).However,there was no statistically significant difference in the positive rate of detection and diagnosis of the above indicators in observation group A and observation group B(P>0.05).Conclusion The combined detection of 5 levels of thyroid function has a significant effect in evaluating thyroid function,and has important guiding significance for the identification and diagnosis of clinical thy⁃roid diseases.
作者 付蓓 王璐 FU Bei;WANG Lu(Department of Laboratory Medicine,Urumqi Traditional Chinese Medicine Hospital,Xinjiang Uygur Autonomous Region,Urumqi,Xinjiang Uygur Autonomous Region,830000 China)
出处 《系统医学》 2022年第16期93-95,123,共4页 Systems Medicine
关键词 甲状腺功能 甲功5项 甲状腺功能亢进 甲状腺功能减退 Thyroid function 5 items of thyroid function Hyperthyroidism Hypothyroidism
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