摘要
目的探讨脓毒症并发急性呼吸窘迫综合征(ARDS)患者预后的影响因素。方法抽取2021年1月至2021年12月河南省人民医院重症监护室收治的脓毒症并发ARDS患者124例,根据预后情况分为观察组(存活,64例)和对照组(死亡,60例)。总结预后危险因素情况,并予以统计学分析。结果两组年龄、合并基础疾病、脓毒症严重程度、急性生理和慢性健康评估Ⅱ(APACHEⅡ)评分、白蛋白水平、尿素水平、急性功能障碍器官数比较,差异有统计学意义(P<0.05)。将前述有差异的因素行多因素分析,结果显示,年龄、合并基础疾病、脓毒症严重程度是脓毒症并发ARDS患者预后的独立危险因素(OR=1.09、2.18、3.92,P均<0.05)。结论脓毒症合并ARDS患者预后的影响因素较多,如年龄、合并基础疾病、脓毒症严重程度、APACHEⅡ评分、白蛋白水平等,但独立危险因素主要为年龄、合并基础疾病、脓毒症严重程度,临床应针对这些因素做好防范。
Objective To investigate the risk factors for prognosis in patients with sepsis complicated by acute respiratory distress syndrome(ARDS).Methods A total of 124 patients with sepsis complicated by ARDS admitted to the intensive care unit of Henan Provincial People’s Hospital from January 2021 to December 2021 were selected.According to the prognosis,they were divided into observation group(survival,64 cases)and control group(death,60 cases).The prognostic risk factors were summarized and analyzed statistically.Results There were significant differences in age,underlying diseases,severity of sepsis,acute physiology and chronic health evaluationⅡ(APACHEⅡ)score,albumin level,urea level,and the number of organs with acute dysfunction between the two groups(P<0.05).Results of multivariate analysis of the above-mentioned factors showed that age,underlying diseases,and severity of sepsis were independent risk factors for the prognosis of patients with sepsis complicated by ARDS(OR=1.09,2.18,3.92;all P<0.05).Conclusions Factors influencing prognosis of patients with sepsis complicated with ARDS include age,underlying diseases,severity of sepsis,APACHEⅡscore,albumin level;but the main independent risk factors include age,morbidity diseases,sepsis severity;moreover,clinical precautions should be taken against these factors.
作者
王明强
赵子瑜
Wang Mingqiang;Zhao Ziyu(Department of Intensive Care Unit,Henan Provincial People’s Hospital,Zhengzhou 450003,China)
出处
《中国实用医刊》
2022年第15期36-39,共4页
Chinese Journal of Practical Medicine
关键词
脓毒症
急性呼吸窘迫综合征
预后
Sepsis
Acute respiratory distress syndrome
Prognosis
