摘要
目的探讨不同时间PICC置管对急性淋巴细胞白血病患者生活质量的影响。方法选取2016年8月至2017年11月收治的40例急性淋巴细胞白血病患者作为研究对象,根据PICC置管时间分为对照组和研究组,每组20例。对照组在进行化疗前进行PICC置管治疗,而研究组则在化疗后15 d置管,比较2组患者置管15 d内不良反应率,血小板、白细胞以及红细胞水平变化、生活质量评分[癌症生命质量测定(FACT-G量表)]。结果研究组不良反应发生率,血小板、白细胞以及红细胞水平低于对照组(P<0.05);入院时2组FACT-G评分差异无统计学意义(P>0.05),置管30 d时研究组FACT-G评分高于对照组(P<0.05)。结论急性淋巴细胞白血病患者化疗后再行PICC置管与化疗前置管对比可降低患者的静脉炎、感染、出血等不良事件,提升生活质量评分。
Objective To investigate the effects of PICC catheterization at different times on the life quality of patients with acute lymphoblastic leukemia(ALL).Methods Forty patients with ALL who were treated in our hospital from August 2016 to November 2017 were enrolled in the study,who were divided into two groups according to the time of PICC catheterization,with 20 cases in each group.The patients in control group were treated by PICC catheterization before chemotherapy,however,those in research group were treated by PICC catheterization after 15d after chemotherapy.The incidence of adverse reaction,and the changes of the levels of platelets,white blood cells and red blood cells,and life quality scores within 15 days were observed and compared between the two groups.Results The incidence of adverse reactions and the levels of platelets,white blood cells and red blood cells in research group were significantly lower than those in control group(P<0.05).On admission there were no significant differences in the FACT-G scores between the two groups(P>0.05).However the FACT-G scores at 30d after catheterization in research group were significantly higher than those in control group(P<0.05).Conclusion As compared with PICC catheterization before chemotherapy,the PICC catheterization after chemotherapy can decrease the incidence rates of adverse events including phlebitis,infection and bleeding,and can improve the life quality scores of patients with ALL.
作者
冒晓敏
刘小莉
殷松花
MAO Xiaomin;LIU Xiaoli;YIN Songhua(Rugao Hospital Affiliated to Nantong University/Department of Hematology of Rugao People’s Hospital,Jiangsu,Rugao 226500,China)
出处
《河北医药》
CAS
2022年第18期2825-2827,共3页
Hebei Medical Journal
