摘要
目的 探讨子宫内膜癌临床病理特征及其与盆腔淋巴结转移的相关性。方法 收集86例行全面分期手术的子宫内膜癌患者的一般资料、病理资料等,如年龄、组织病理类型、组织分化程度、肌层浸润深度、宫颈受累、子宫外转移及癌灶大小,分析其与子宫内膜癌盆腔淋巴结转移的关系。结果 单因素分析结果显示,组织病理类型、肌层浸润深度、宫颈受累、子宫外转移、腹水脱落细胞学、肿瘤标志物CA125水平、ER、PR、年龄、癌灶大小、组织分化程度与盆腔淋巴结转移相关(P<0.05),与P53阳性表达无关(P>0.05)。多因素分析显示,子宫外转移、病理类型、肌层浸润深度均是盆腔淋巴结转移的独立影响因素(P<0.05),OR值分别为5.298、4.353、3.911。结论 组织病理类型、肌层浸润深度、宫颈受累、子宫外转移、腹水脱落细胞学、肿瘤标志物CA125水平、ER、PR、年龄、癌灶大小、组织分化程度均为子宫内膜癌盆腔淋巴结转移的影响因素,其中子宫外转移、病理类型、肌层浸润均属于重要的独立影响因素。
Objective To investigate the clinicopathological features of endometrial carcinoma and its correlation with pelvic lymph node metastasis.Methods A total of 86 patients with endometrial cancer were collected,all of whom underwent comprehensive staging surgery.General information and pathological data of 86 patients were collected,such as age,histopathological type,degree of tissue differentiation,depth of muscularinfiltration,cervical involvement,extrauterine metastasis and size of cancer foci.Its relation with pelvic lymph node metastasis in endometrial carcinoma was analyzed.Results Univariate analysis showed that histopathological type,depth of muscularinfiltration,cervical involvement,extrauterine metastasis,ascites abscission cytology,tumor marker CA125 level,ER,PR,age,tumor focal size,and degree of tissue differentiation were correlated with pelvic lymph node metastasis(P0.05).Multivariate analysis showed that extrauterine metastasis,pathological type and muscularity were independent factors for pelvic lymph node metastasis(P<0.05),OR values were 5.298,4.353 and 3.911,respectively.Conclusions Histopathologic type,muscular infiltration depth,cervical involvement,extrauterine transfer,ascites cytology and tumor marker CA125 levels,ER,PR,age,and the size of the cancer,tissue differentiation degree are the influence factors of endometrial cancer pelvic lymph node metastasis,which transfer outside the uterus,pathological type,muscular infiltration are important independent risk factors.
作者
李聘
桑玉珍
郭君红
郭玉琪
LI Pin;SANG Yuzhen;GUO Junhong(Kaifeng Maternity Hospital,Kaifeng,475000)
出处
《实用癌症杂志》
2022年第10期1713-1715,共3页
The Practical Journal of Cancer
关键词
子宫内膜癌
盆腔淋巴结转移
影响因素
Endometrial carcinoma
Pelvic lymph node metastasis
Influencing factors
