摘要
目的:探讨CBT干预联合盐酸哌甲酯片在多动症患儿治疗中的应用。方法:选取180例自本院2019年1月~2022年1月收治的多动症患儿,按照随机数字表法分为对照组和观察组,各90例。对照组采用盐酸哌甲酯片,观察组在以上基础上CBT干预治疗,两组患者治疗12周,并随访1周。比较两组患者治疗前后脑电图异常率、Conners量表、血清25-羟维生素D3、多巴胺水平以及主要症状积分,治疗后临床疗效。结果:治疗后观察组临床总有效率明显高于对照组;治疗后两组患者脑电图总异常率、主要症状积分以及Conners量表各项评分均低于治疗前,且观察组低于对照组,血清25-羟维生素D3、多巴胺水平则升高,且观察组高于对照组。结论:多动症患儿采用CBT干预联合盐酸哌甲酯片可有效提高患儿的临床治疗效果,改善其临床症状及表现,促进其神经学损伤的恢复。
Objective To explore the application of CBT intervention combined with methylphenidate hydrochloride tablets in the treatment of children with adhd.Methods One hundred and eighty children with ADHD who were admitted to our hospital from January 2019 to January 2022 were divided into the control group and the observation group,and were divided into 90 cases in each group according to the random number table.Patients in the control group were treated with methylphenidate hydrochloride tablets,while those in the observation group were treated with CBT intervention on the basis of the above.The patients in the two groups received 12 weeks of treatment and were followed up for 1 week.The abnormal rate of electroencephalogram,Conners scale,serum 25-hydroxyvitamin D3,dopamine level and main symptom scores before and after treatment were compared between the two groups.The clinical efficacy after treatment was also compared.Results After treatment,compared with the control group,the total clinical effective rate in the observation group was higher;Compared with those before treatment,the total abnormal rate of electroencephalogram,the main symptom scores and Conners scale scores in the two groups decreased after treatment,and the values in the observation group were lower than those in the control group.The serum 25-hydroxyvitamin D3 and dopamine levels increased,and the values in the observation group were higher than those in the control group,statistically significant differences.Conclusion For the treatment of children with ADHD,CBT intervention combined with methylphenidate hydrochloride tablets can effectively improve the clinical therapeutic effect,clinical symptoms and manifestations,and the recovery of neurological damage.
作者
宋蓓
王萍
陈巍巍
戴园园
Song Bei;Wang Ping;Chen Wei-wei;Dai Yuan-yuan(Department of Pediatrics,Affiliated Hospital of Xuzhou Medical University,Xuzhou 221004,China;Department of Neurology,Xuzhou Clinical College,affiliated to Xuzhou Medical University,Xuzhou 221004,China;Clinic of No.36 middle school,Xuzhou 221008,China)
出处
《湖南师范大学学报（医学版）》
2022年第4期65-69,共5页
Journal of Hunan Normal University(Medical Sciences)
基金
国家自然科学青年基金资助项目(81501138)。
关键词
多动症
盐酸哌甲酯
认知行为疗法
临床效果
ADHD
Methylphenidate hydrochloride
Cognitive behavioral therapy
Clinical effects
