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前列腺等离子剜除术联合钬激光碎石术治疗良性前列腺增生合并膀胱结石的疗效探究 被引量:4

Efficacy of Plasma Enucleation of Prostate Combined with Holmium Laser Lithotripsy in the Treatment of Benign Prostatic Hyperplasia Complicated with Bladder Stones
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摘要 目的分析经尿道等离子前列腺剜除术(transurethral plasmakinetic resection of prostate,PKEP)与钬激光碎石术联合应用于良性前列腺增生(benign prostatic hyperplasia,BPH)合并膀胱结石临床治疗中的效果及价值。方法回顾性分析烟台市莱阳中心医院于2018年1月—2021年10月接收的100例BPH合并膀胱结石患者的临床资料,按照治疗方式的不同将其分为参照组[n=50,实施经尿通前列腺电切术(trans urethral resection prostate,TURP)治疗]和观察组(n=50,开展PKEP联合钬激光碎石术治疗),观察和比较治疗后两组患者的临床疗效和并发症。结果观察组术中出血量、手术时长、住院时长、导尿管留置时间、膀胱冲洗时间低于参照组,差异有统计学意义(P<0.05)。术后3个月两组患者的生存质量评分(QOL)、国际前列腺症状评分(IPSS)、残余尿量(RUV)均得到不同程度降低,且观察组明显低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者的Qmax明显升高,且观察组明显高于参照组,差异有统计学意义(P<0.05)。两组患者结石残余率比较(2.00%vs 4.00%),差异无统计学意义(P>0.05)。观察组并发症发生率(6.00%)明显低于参照组(24.00%),差异有统计学意义(χ^(2)=6.353,P<0.05)。结论在BPH合并膀胱结石的临床治疗中使用PKEP与钬激光碎石术联合治疗的方式患者手术效率显著提升,手术时间明显缩短,患者术后恢复良好,较为安全有效。 Objective To analyze the effect and value of transurethral plasma enucleation of the prostate(PKEP)combined with holmium laser lithotripsy in the clinical treatment of benign prostatic hyperplasia(BPH)complicated with bladder stones.Methods The clinical data of 100 patients with BPH complicated with bladder stones received in Yantai Laiyang Central Hospital from January 2018 to October 2021 were retrospectively analyzed.According to the different treatment methods,they were divided into the control group(n=50,treated with transurethral resection of the prostate TURP)and the observation group(n=50,treated with PKEP combined with holmium laser lithotripsy).The clinical efficacy and complications of the two groups of patients after treatment were observed and compared.Results The intraoperative blood loss,operation time,hospitalization time,catheter indwelling time,and bladder irrigation time in the observation group were significantly lower than those in the control group,and the difference was statistically significant(P<0.05).The Quality of Life Score(QOL),International Prostate Symptom Score(IPSS),and Residual Urine Volume(RUV)of the two groups of patients were reduced to varying degrees 3 months after surgery,and the observation group were significantly lower than the control group,and the difference was statistically significant(P<0.05).After treatment,the Qmax of the two groups of patients was significantly increased,and the observation group was significantly higher than the control group,and the difference was statistically significant(P<0.05).The residual stone rate in the two groups was similar(2.00%vs 4.00%),and the difference was not statistically significant(P>0.05).the incidence of complications of the observation group(6.00%)was significantly lower than the control group(24.00%),and the difference was statistically significant(χ^(2)=6.353,P<0.05).Conclusion In the clinical treatment of BPH complicated with bladder stones,the combined treatment of PKEP and holmium laser lithotripsy significantly improves the operative efficiency,shortens the operative time,and recovers well after surgery,which is safe and effective.
作者 姜升旭 JIANG Shengxu(Department of Urology,Yantai Laiyang Central Hospital,Yantai,Shandong Province,265200 China)
出处 《系统医学》 2022年第18期116-120,共5页 Systems Medicine
关键词 膀胱结石 良性前列腺增生 钬激光碎石术 PKEP 并发症 Bladder stones Benign prostatic hyperplasia Holmium laser lithotripsy PKEP Complications
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