摘要
鼻内镜鼻窦手术(ESS)已成为外科治疗慢性鼻窦炎伴鼻息肉(CRSwNP)的“金标准”,鼻内镜鼻窦手术围手术期管理对手术效果有重要影响。目前口服糖皮质激素因其抗炎和免疫抑制作用已作为ESS围术期辅助用药以增强手术效果,但在其剂量剂型及疗效等方面仍存在争议。回顾近年来研究口服糖皮质激素与CRSwNP围手术期疗效的相关文献,对口服糖皮质激素在围手术期的效果及治疗策略进行综述,以求提供更多的治疗选择和研究方向。
Endoscopic sinus surgery(ESS)has become the“gold standard”for the surgical treatment of chronic rhinosinusitis with nasal polyps(CRSwNP).The perioperative management of ESS has an important influence on the results of surgery.At present,oral glucocorticoids have been used as ESS perioperative adjuvant drugs to enhance the surgical effect due to their anti-inflammatory and immunosuppressive effects.However,there are still controversies related to their dosage form and efficacy.This article reviews the recent studies on oral glucocorticoids and CRSwNP-related literature on perioperative efficacy.The effects and treatment strategies of oral glucocorticoids during the perioperative period have been reviewed to provide more treatment options and research directions.
作者
资昊坤(综述)
肖旭平
李云秋(审校)
ZI Haokun;XIAO Xuping;LI Yunqiu(Department of Otorhinolaryngology&Head and Neck Surgery,the First Affiliated Hospital of Hunan Normal University/Hunan Provincial People's Hospital,Changsha 410005,Hunan,China)
出处
《山东大学耳鼻喉眼学报》
CAS
2022年第3期98-103,共6页
Journal of Otolaryngology and Ophthalmology of Shandong University
关键词
鼻窦炎
鼻息肉
糖皮质激素
鼻内镜手术
Sinusitis
Nasal Polyps
Glucocorticoids
Endoscopic surgery