摘要
目的分析1023例肾脏疾病患者的肾组织活检病理类型。方法回顾性选取2015年7月1日至2021年6月30日就诊于济宁市第一人民医院肾内科并行肾穿刺活检的所有患者作为研究对象。按照接受肾穿刺活检时间将研究对象分为组1(2015年7月1日至2018年6月30日)和组2(2018年7月1日至2021年6月30日);研究对象又根据年龄分为儿童组(<20岁)、青年组(20~<40岁)、中年组(40~<60岁)和老年组(≥60岁),分析其各组临床资料特点并比较组1、组2病理类型变化。结果1023例研究对象中接受肾活检时年龄集中在青年组、中年组。研究对象中男性575例(56.3%),女性448例(43.7%),差异有统计学意义(P<0.05)。组1系膜增生性肾小球肾炎、高血压肾病占比与组2比较明显减少,差异有统计学意义(P<0.05),两组中原发性肾小球疾病患者最常见的病理类型为膜性肾病(511例,49.9%),其次为IgA肾病(180例,17.6%);继发性肾小球疾病患者中过敏性紫癜性肾炎(44例,4.3%)和狼疮性肾炎(44例,4.3%)为较常见病理类型。结论1023例研究对象以青中年男性人群为主,在病理类型上以膜性肾病及过敏性紫癜性肾炎最常见。
Objective To analyze the pathological types of renal biopsy in 1023 patients with kidney disease.Methods All patients who underwent renal biopsy in the department of Nephrology,Jining NO.1 People′s Hospital from July 1,2015 to June 30,2021 were retrospectively selected as the research objects.The research objects were divided into group 1(from July 1,2015 to June 30,2018)and group 2(from July 1,2018 to June 30,2021)according to the time of receiving renal biopsy.The subjects were further divided into children group(<20 years old),young group(20-<40 years old),middle-aged group(40-<60 years old)and elderly group(≥60 years old)according to their age.The clinical characteristics of each group were analyzed and the pathological types of group 1 and group 2 were compared.Results Among the 1023 subjects,the age of receiving renal biopsy was concentrated in the young group and the middle-aged group.There were 575 males(56.3%)and 448 females(43.7%),the difference was statistically significant(P<0.05).The proportion of mesangial proliferative glomerulonephritis and hypertensive nephropathy in group 1 was significantly lower than that in group 2,the difference was statistically significant(P<0.05).The most common pathological type of primary glomerular disease in the two groups was membranous nephropathy(511 cases,49.9%),followed by IgA nephropathy(180 cases,17.6%).Henoch-schonlein purpura nephritis(n=44,4.3%)and lupus nephritis(n=44,4.3%)were the more common pathologic types in patients with secondary glomerular disease.Conclusion The 1023 subjects are mainly young and middle-aged men.The most common pathological type is membranous nephropathy and henoch-schonlein purpura nephritis.
作者
王文文
周世菊
WANG Wenwen;ZHOU Shiju(Clinical Medical College of Jining Medical University,Jining,Shandong 272000,China;Department of Nephrology,Jining NO.1 People′s Hospital,Jining,Shandong 272000,China)
出处
《检验医学与临床》
CAS
2022年第21期2976-2979,共4页
Laboratory Medicine and Clinic
