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转化生长因子β1与支气管肺发育不良关系的研究进展

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摘要 支气管肺发育不良(Bronchopulmonary dysplasia,BPD)是由于早产儿肺发育不成熟和出生前后自身或外界因素共同作用(如高氧、感染、机械通气等)导致的肺和支气管的异常发育。随着新生儿医学研究的深入以及围产辅助生殖水平的提高,早产儿存活率明显升高,尤其是超早产儿,故使得BPD的发病率增高。胎龄22~28周超早产儿近40%有发展为BPD的风险,是死亡和长期呼吸、神经发育残疾的主要儿科就诊原因[1]。临床上引起BPD的病因较多,不同病因引起的BPD病理生理改变、临床表现及预后不同[2]。
出处 《中国现代医药杂志》 2022年第10期96-100,共5页 Modern Medicine Journal of China
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