摘要
目的分析人绒毛膜促性腺激素序贯疗法对低促性腺激素性闭经致不孕不育患者性激素水平及妊娠率的影响。方法选取2019年2月至2021年7月我院不孕不育患者78例,随机分为研究组和常规组,各组39例。常规组予以人工月经周期联合尿促性腺激素肌肉注射,研究组予以人绒毛膜促性腺激素序贯疗法。对比两组疗效、性激素[促卵泡素(FSH)、催乳素(PRL)、孕酮(P)]水平、子宫内膜厚度及妊娠成功率。结果研究组总有效率94.87%(37/39)较常规组76.92%(30/39)高(P<0.05);治疗后,研究组FSH、LH、PRL、P水平较常规组高(P<0.05);治疗后,研究组子宫内膜厚度较常规组厚(P<0.05);研究组妊娠成功率89.74%(35/39)较常规组71.79%(28/39)高(P<0.05)。结论人绒毛膜促性腺激素序贯疗法对低促性腺激素性闭经致不孕不育患者效果确切,可加快妊娠。
Objective To analyze the effect of human chorionic gonadotropin sequential therapy on sex hormone levels and pregnancy rate in infertility patients with low gonadotropin-induced amenorrhea.Methods 78 infertility patients from February 2019 to July 2021 were randomly divided into study group and conventional group,with 39 patients in each group.The conventional group gave artificial menstrual cycle combined with urinary gonadotropin intramuscular injection,and the research group gave human chorionic gonadotropin sequential therapy.The efficacy of the two groups,sex hormone[follicle stimulating hormone(FSH),prolactin(PRL),progesterone(P)]levels,endometrial thickness and pregnancy success rate were compared.Results The total response rate of the study group was 94.87%(37/39):76.92%(30/39)(P<0.05);after treatment,FSH,LH,PRL and P(P<0.05),endometrial thickness(P<0.05),and the pregnancy success rate was 89.74%(35/39):71.79%(28/39)(P<0.05).Conclusion Continuous therapy in infertility patients with low gonadotropin amenorrhea can accelerate pregnancy.
作者
李洁
LI Jie(Department of Gynecology,Xincai County Maternal and Child Health Care Hospital,Xincai 463500,Henan Province,China)
出处
《罕少疾病杂志》
2022年第11期93-94,共2页
Journal of Rare and Uncommon Diseases
