摘要
目的探析弥散加权成像(DWI)联合动态增强磁共振扫描(DCE-MRI)评估前列腺病变性质的价值。方法选取河南科技大学第一附属医院2019年1月至2021年12月收治的拟接受手术治疗的65例前列腺疾病患者作为研究对象,患者均接受DWI、DCE-MRI检查,并以组织病理学检查结果作为金标准,探析DWI联合DCE-MRI评估前列腺病变性质的价值。结果以组织病理学检查结果作为金标准,65例患者中良性组41例(63.08%),其中前列腺炎24例,前列腺增生17例;恶性组24例(36.92%),其中小细胞癌12例,黏液腺癌10例,导管腺癌2例;b值为1000 s·mm^(-2)时恶性组融合表观扩散系数(ADC)值高于良性组(P<0.05);恶性组K^(trans)、K_(ep)高于良性组(P<0.05);进一步绘制受试者工作特征(ROC)曲线,结果显示,ADC、K^(trans)、K_(ep)单独及联合定性评估前列腺病变患者的曲线下面积(AUC)均>0.7,且三者联合检查的评估价值最高。结论DWI联合DCE-MRI检查可有效评估前列腺疾病患者病变性质,且两者联合评估价值更高。
Objective To evaluate the value of diffusion weighted imaging(DWI)combined with dynamic diffusion weighted MRI(DCE-MRI)in evaluating the nature of prostate lesions.Methods A total of 65 patients with prostate diseases who prepared to receive surgical treatment in the First Affiliated Hospital of Henan University of Science and Technology from January 2019 to December 2021 were selected as the research subjects.All patients were treated with DWI and DCE-MRI,and the histopathological results were used as the gold standard to explore the value of DWI combined with DCE-MRI in evaluating the nature of prostate lesions.Results According to the results of histopathological examination as the gold standard,among 65 patients,41 patients(63.08%)were benign,including 24 cases of prostatitis and 17 cases of benign prostatic hyperplasia.The malignant group consisted of 24 cases(36.92%),including 12 cases of small cell carcinoma,10 cases of mucinous adenocarcinoma,and 2 cases of ductal adenocarcinoma.When the b value was 1000 s·mm^(-2),the apparent diffusion coefficient(ADC)value in malignant group was higher than that in benign group(P<0.05).K^(trans) and K_(ep) in malignant group were higher than those in benign group(P<0.05).Further drew the receiver operating characteristic(ROC)curve,and the results showed that,the area under curve(AUC)area of ADC value,K^(trans),K_(ep) alone and combined qualitative evaluation of patients with prostate lesions were>0.7,and the combined evaluation value of the three was the highest.Conclusion DWI combined with DCE-MRI can effectively evaluate the nature of lesions in patients with prostate diseases,and the combined evaluation value of both is higher.
作者
张丹卉
史展
ZHANG Danhui;SHI Zhan(Imaging Center,the First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,China)
出处
《河南医学研究》
CAS
2022年第21期3994-3997,共4页
Henan Medical Research
关键词
前列腺病变
弥散加权成像
动态增强磁共振扫描
prostate lesions
diffusion weighted imaging
dynamic contrast enhanced magnetic resonance imaging
