摘要
虽然头颈部结构微细复杂,但高分辨率MRI显著提高了头颈部结构和病变的显示能力。本文论述了定量MRI在视神经炎、甲状腺相关性眼病、视网膜母细胞瘤侵犯筛板后视神经、鼻咽癌、口咽癌、喉癌、甲状腺癌、鼻腔鼻窦内翻性乳头状瘤、涎腺多形性腺瘤、淋巴瘤和炎性假瘤等头颈部疾病的显示与评估、鉴别诊断、分期与分级、疗效评估与预测、预后预测以及发生机制研究方面的作用,并阐明了存在的问题与未来解决思路。未来建议严格做好临床研究设计,确定纳入和排除标准,按照统一的诊断、评估和预测标准,以患者为中心、以临床问题为导向,开展全国多中心大样本量前瞻性研究,进一步提升定量MRI在头颈部疾病诊疗中的价值,并在临床推广应用,提高诊疗水平,保障人民健康。
The anatomic structures in head and neck are tiny and complex, but high resolution MRI significantly improve the diagnostic performance of MRI in the demonstration of anatomic structures and lesions in head and neck region. Quantitative MRI plays an important role in the identification, diagnosis, stage, grade, evaluation of treatment response, and prediction of prognosis as well as elucidation of the pathological mechanisms of head and neck diseases, such as optic neuritis, thyroid-associated ophthalmopathy, post-laminar optic nerve invasion from retinoblastoma, nasopharyngeal carcinoma, oropharyngeal carcinoma, laryngeal carcinoma, thyroid carcinoma, sinonasal inverted papilloma, pleomorphic salivary adenoma, lymphoma, inflammatory pseudotumor, etc. The problems and the problem-solving strategies are also described. In the future, the study design will be conducted strictly with inclusion and exclusion criteria defined. According to the same criteria of the diagnosis, evaluation, and prediction of the head and neck diseases, national large-sample multicenter prospective researches will be developed so as to establish patient-centered and problem-guided protocols of quantitative MRI of the head and neck diseases. These protocols will further improve the value of quantitative MRI in the diagnosis and treatment of head and neck diseases, which will be applied nationwide promoting diagnosis and treatment of head and neck diseases and protecting people’s health.
作者
鲜军舫
XIAN Junfang(Department of Radiology,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2022年第11期1-5,共5页
Chinese Journal of Magnetic Resonance Imaging
基金
国家自然科学基金(编号:81871340、82071906、82202100、81571649)
北京市医院管理局临床医学发展专项(编号:ZYLX201704)
北京市医院管理中心“登峰”计划专项(编号:DFL20190203)。
关键词
视神经炎
甲状腺相关性眼病
视网膜母细胞瘤
鼻咽癌
口咽癌
喉癌
甲状腺癌
内翻性乳头状瘤
多形性腺瘤
淋巴瘤
炎性假瘤
青光眼
磁共振成像
动态对比增强
扩散加权成像
动脉自旋标记
诊断
疗效评价
发病机制
预后预测
optic neuritis
thyroid-associated ophthalmopathy
retinoblastoma
nasopharyngeal carcinoma
oropharyngeal carcinoma
laryngeal carcinoma
thyroid carcinoma
inverted papilloma
pleomorphic adenoma
lymphoma
inflammatory pseudotumor
glaucoma
magnetic resonance imaging
dynamic contrast enhancement
diffusion weighted imaging
arterial spin labeling
diagnosis
treatment response evaluation
pathological mechanism
prognosis prediction
