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帕洛诺司琼联合氟哌利多预防地佐辛妇科腔镜术后镇痛期间恶心呕吐的临床研究 被引量:1

Clinical study of palonosetron combined with droperidol in the prevention of nausea and vomiting during analgesia with dezocine after gynecological endoscopy
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摘要 目的 探讨帕洛诺司琼联合氟哌利多预防地佐辛妇科腔镜术后镇痛期间恶心呕吐的临床效果。方法 选择60例子宫肌瘤患者,使用随机数字表法分为氟哌利多组(F组)、帕洛诺司琼组(P组)、帕洛诺司琼+氟哌利多(PF组),各20例。对比三组患者术后24 h时恶心、呕吐程度和头晕程度及治疗有效率。结果 P组和PF组恶心、呕吐程度均低于F组,F组和PF组头晕程度均低于P组,PF组治疗有效率和完全控制率较P组与F组更高,差异有统计学意义(P<0.05)。结论 单独应用帕洛诺斯琼即可达到较理想的止吐效果,但是复合氟哌利多可在镇吐的同时,也能减轻地佐辛带来的头晕不适,提高患者治疗满意度。 Objective To investigate the clinical effect of palonosetron combined with droperidol in the prevention of nausea and vomiting during postoperative analgesia with dezocine gynecological endoscopy.Methods 60 patients with uterine fibroids were selected and divided into droperidol group(group F),palonosetron group(group P),and palonosetron + droperidol(group PF)by random number table method.20 cases in each group.The degree of nausea,vomiting and dizziness of the three groups of patients at 24 hours after operation,as well as the treatment efficiency and satisfaction were compared.Results The degree of nausea and vomiting in group P and PF were lower than those in group F,the degree of dizziness in group F and group PF were lower than that in group P,and the treatment effective rate and complete control rate of group PF were higher than those of group P and group F,and the difference was statistically significant Significance(P<0.05).Conclusion Palonosetron alone can achieve ideal antiemetic effect,but compound droperidol can also reduce dizziness and discomfort caused by dezocine and improve the treatment satisfaction of patients.
作者 王琳琳 Wang Linlin(Department of Anesthesiology,The Second Clinical Medical College of Jinan University,Shenzhen 518020,China)
出处 《实用妇科内分泌电子杂志》 2021年第20期66-68,共3页 Electronic Journal of Practical Gynecological Endocrinology
关键词 腹腔镜手术 帕洛诺司琼 氟哌利多 地佐辛 Laparoscopic surgery Palonosetron Droperidol Dezocine
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