摘要
视网膜血管的结构和形态是计算机辅助系统诊断眼科疾病的重要依据.针对细小血管分割精度低的问题,提出一种融合残差密集模块与三端注意力模块的改进型U-Net算法.首先,将残差模块与密集模块相结合,充分利用每层的特征,提高网络提取细小血管特征的能力.在解码阶段引入三端注意力模块,利用空间注意力机制自适应地对特征进行空间校正,抑制背景噪声,突出目标区域.同时,通过多尺度特征融合的方式,利用高级语义特征改善网络对细小血管的分割效果.最后,为获取血管的多尺度特征,在编码-解码网络结构中加入空洞卷积,在不增加参数的情况下增加感受野.基于DRIVE和STARE数据集的实验结果表明,所提出网络的灵敏度、特异性、准确率和AUC(area under curve)分别为81.26%/82.57%、98.20%/98.37%、96.70%/97.51%和98.12%/98.41%,优于现有先进算法.
The structure and morphology of retinal blood vessels are essential for computer-aided systems to diagnose ophthalmological diseases.To solve the problem of low precision of tiny blood vessel segmentation,we propose an improved U-Net algorithm combining a residual dense block and a three-terminal attention gate block.First of all,we combine the residual block with the dense block to make full use of the features of each layer and improve the ability to extract the characteristics of tiny blood vessels.In the decoding stage,we introduce a three-terminal attention gate block.And the spatial attention mechanism is used to adaptively correct the features,suppress background noise and highlight the target area.At the same time,we use high-level semantic features to improve the segmentation effect of tiny blood vessels through multi-scale feature fusion.Finally,to obtain the multi-scale features of blood vessels,we introduce deformable convolution into the network structure and increase the receptive field without increasing the parameters.The experimental results based on the DRIVE and STARE data sets show that the sensitivity,specificity,accuracy and AUC(area under curve)of the proposed network are 81.26%/82.57%、98.20%/98.37%、96.70%/97.51%and98.12%/98.41%,which are better than existing advanced algorithms.
作者
曹飞道
赵怀慈
CAO Fei-dao;ZHAO Huai-ci(Key Laboratory of Opto-Electronic Information Process,Chinese Academy of Sciences,Shenyang 110016,China;Shenyang Institute of Automation,Chinese Academy of Sciences,Shenyang 110016,China;Institutes for Robotics and Intelligent Manufacturing,Chinese Academy of Sciences,Shenyang 110169,China;University of Chinese Academy of Sciences,Beijing 100049,China)
出处
《控制与决策》
EI
CSCD
北大核心
2022年第10期2505-2512,共8页
Control and Decision
基金
国家自然科学基金项目(62041302)。
关键词
计算机辅助系统
血管分割
U-Net
残差密集模块
空洞卷积
三端注意力模块
computer-aided system
vessel segmentation
U-Net
residual dense block
deformable convolution
threeterminal attention gate block
