摘要
目的探讨液基薄层细胞学联合高危型人乳头瘤病毒(HPV)-DNA检测在宫颈癌筛查中的应用效果。方法选取260例受检者,实施宫颈液基薄层细胞学检测、高危型HPV-DNA检测,以病理活检作为金标准,比较检测效果。结果液基薄层细胞学联合高危型HPV-DNA检测优于单一检测,差异有统计学意义(P<0.05)。高危型HPV-DNA检测诊断率低于液基薄层细胞学检测,差异有统计学意义(P<0.05)。高危型HPV-DNA检测诊断率低于病理活检,差异有统计学意义(P<0.05)。结论液基薄层细胞学联合高危型HPV-DNA检测可提高宫颈癌检出准确率,具有显著的应用价值,可为疾病后期诊治提供可靠的参考及借鉴。
Objective To investigate the application effect of liquid-based thin-layer cytology combined with high-risk human papillomavirus(HPV)-DNA detection in cervical cancer screening.Methods 260 subjects were selected and tested by cervical fluid-based thin-layer cytology and high-risk HPV-DNA.Pathological biopsy was used as the gold standard to compare the detection effect.Results Liquid-based thin-layer cytology combined with high-risk HPV-DNA detection was better than single detection,and the difference was statistically significant(P<0.05).The diagnostic rate of high-risk HPV-DNA test was lower than that of liquid-based thin-layer cytology test,and the difference was statistically significant(P<0.05).The detection rate of high-risk HPV-DNA was lower than that of pathological biopsy,and the difference was statistically significant(P<0.05).Conclusion Liquid-based thin-layer cytology combined with high-risk HPV-DNA detection can improve the detection accuracy of cervical cancer,which has significant application value,and can provide reliable reference for the later diagnosis and treatment of the disease.
作者
蒋爱荣
Jiang Airong(Department of Gynecology,The Second Branch of Huai'an First People's Hospital,Huai'an 223000,China)
出处
《实用妇科内分泌电子杂志》
2021年第31期86-88,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
宫颈癌
宫颈液基薄层细胞学检测
高危型人乳头瘤病毒-DNA检测
Cervical cancer
Cervical fluid based thin layer cytology detection
High-risk human papillomavirus-DNA testing
