摘要
本文通过选用液相色谱-串联质谱法同时测定水产品中呋喃唑酮、呋喃西林、呋喃妥因3种药物的代谢残留。提取溶剂为0.1%甲酸-乙腈溶液,涡旋超声提取,采用固相萃取柱(CNW POLY-SERY MCX)净化,经ACQUITY UPLC BEH C_(18)色谱柱分离,以乙酸胺和甲醇溶液进行梯度洗脱。采用正模式ESI源,定量检测选用多重反应模式。
In this paper,liquid chromatography-tandem mass spectrometry was used to simultaneously determine the residues of furazolidone,furacillin and furantoin in aquatic products.The extraction solvent was 0.1%formic acid and acetonitrile solution,and the extraction was carried out by vortex ultrasonic extraction.The purification was performed on a solid-phase extraction column(CNW POLY-SERY MCX),and the separation was performed on an ACQUITY UPLC BEH C_(18) column.The gradient elution was performed with acetic acid and methanol solution.Positive mode ESI source was used,and multiple reaction mode was used for quantitative detection.
作者
吴刚
WU Gang(The Second Station of Ningxia Food Quality Supervision and Inspection,Yinchuan 750001,China)
出处
《食品安全导刊》
2022年第32期70-74,共5页
China Food Safety Magazine
关键词
水产品
液相色谱-串联质谱法
硝基呋喃类代谢物
aquatic products
liquid chromatography-tandem mass spectrometry
nitrofuran metabolites
