摘要
目的调查并分析药源性呃逆的药物种类及临床特点。方法在中国知网、中国医院数字图书馆和中华医学期刊全文数据库平台,以“呃逆”、“膈肌痉挛”、“药源性呃逆”、“打嗝”为关键词,检索从建库至2021年12月31日的相关文献,进行回顾性分析。结果共检索出224篇,报道药物所致呃逆1010例,共96种药物,主要为抗菌药物和肾上腺皮质激素。其中男851例,女159例,男女比例为5.35∶1,分布于各年龄段。结论引起呃逆的药物种类多样,主要为糖皮质激素地塞米松和抗菌药物,男性多发,具体机制有待研究。
Objective To investigate and analyze the types of drugs and clinical characteristics of drug-induced hiccup.Methods Related literatures from the establishment of the database to December 31,2021 were retrieved on CNKI,Digital Library of China Hospital and Full-text database of Chinese Medical Journals using the keywords"hiccup","diaphragmic spasm","drug-induced hiccup"and"hiccup".Results A total of 224 articles were retrieved,1010 cases of hiccup caused by drugs were reported.96 kinds of drugs,mainly antibiotics and adrenal corticosteroids.There were 851 males and 159 females,with a male to female ratio of 5.35∶1,distributed in all ages.Conclusion There are various kinds of drugs causing hiccup,including glucocorticoid dexamethasone and antibiotics.Males are more common,and the specific mechanism remains to be studied.
作者
赵娜
陈敏
王瑞娜
王冉
李圳
任翠翠
朱舒虹
ZHAO Na;CHEN Min;WANG Ruina;WANG Ran;LI Zhen;REN Cuicui;ZHU Shuhong(The First Affiliated Hospital of Northwestern University/the First Hospital of Xi'an,Xi'an,Shaanxi 710001,China)
出处
《检验医学与临床》
CAS
2022年第S02期77-80,共4页
Laboratory Medicine and Clinic
关键词
呃逆
膈肌痉挛
药源性呃逆
打嗝
hiccup
diaphragmatic spasm
drug-induced hiccup
burp
