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呼吸湿化治疗仪联合肺康复治疗COPD合并Ⅱ型呼吸衰竭的临床研究 被引量:6

Clinical Study of Respiratory Humidification Therapy Apparatus Combined with Pulmonary Rehabilitation in the Treatment of COPD Complicated With TypeⅡRespiratory Failure
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摘要 目的:探讨分析呼吸湿化治疗仪联合肺康复治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭患者的效果。方法:回顾性分析2019年1月-2021年7月肇庆市第一人民医院收治的90例确诊为COPD合并Ⅱ型呼吸衰竭患者的临床资料,根据治疗方式将患者分成三组,A组(n=28)、B组(n=42)、C组(n=20)。A组给予呼吸湿化治疗仪治疗,B组给予呼吸湿化治疗仪+呼吸兴奋剂治疗,C组给予呼吸湿化治疗仪+肺康复治疗。比较三组血气指标[酸碱度(pH)、血氧分压(PaO_(2))、血二氧化碳分压(PaCO_(2))、动脉血氧含量(SaO_(2))]、呼吸频率和心率、ICU住院率和插管率。结果:治疗前,三组PaO_(2)、PaCO_(2)、SaO_(2)水平比较,差异均无统计学意义(P>0.05);治疗后3 d,三组pH值与治疗前比较,差异均无统计学意义(P>0.05);治疗后3 d,三组PaO_(2)、PaCO_(2)、SaO_(2)水平均优于治疗前,且C组均优于A组和B组,B组均优于A组,差异均有统计学意义(P<0.05)。治疗前,三组呼吸频率和心率比较,差异均无统计学意义(P>0.05);治疗后3 d,三组呼吸频率和心率均低于治疗前,且C组均低于A组和B组,B组均低于A组,差异均有统计学意义(P<0.05)。C组ICU住院率和插管率均低于A组和B组,差异均有统计学意义(P<0.05)。结论:呼吸湿化治疗仪联合肺康复治疗COPD合并Ⅱ型呼吸衰竭患者可改善呼吸功能,恢复心率,降低ICU住院率和插管率,促进患者恢复,值得推广。 Objective:To explore and analyze the effect of respiratory humidification therapy apparatus combined with pulmonary rehabilitation in the treatment of patients with chronic obstructive pulmonary disease(COPD)complicated with typeⅡrespiratory failure.Method:The clinical data of 90 patients with COPD complicated with typeⅡrespiratory failure admitted to the First People’s Hospital of Zhaoqing from January 2019 to July 2021 were retrospectively analyzed,according to the treatment methods,the patients were divided into three groups:group A(n=28),group B(n=42)and group C(n=20).Group A was treated with respiratory humidification therapy apparatus,group B was treated with respiratory humidification therapy apparatus+respiratory stimulant therapy,and group C was treated with respiratory humidification therapy apparatus+pulmonary rehabilitation therapy.Blood gas indexes[pondus hydrogenii(pH),partial pressure of oxygen(PaO_(2)),partial pressure of carbon dioxide(PaCO_(2)),arterial oxygen content(SaO_(2))],respiratory rate and heart rate,ICU hospitalization rate and intubation rate were compared among the three groups.Result:Before treatment,there were no significant differences in the levels of PaO_(2),PaCO_(2) and SaO_(2) among the three groups(P>0.05);at 3 d after treatment,there were no significant differences in pH among the three groups compared with those before treatment(P>0.05);at 3 d after treatment,the levels of PaO_(2),PaCO_(2),and SaO_(2) in the three groups were better than those before treatment,those in the group C were better than those in the group A and group B,those in the group B were better than those in the group A,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in respiratory rate and heart rate among the three groups(P>0.05);at 3 d after treatment,the respiratory rate and heart rate in the three groups were lower than those before treatment,those in the group C were lower than those in the group A and group B,those in the group B were lower than those in the group A,the differences were statistically significant(P<0.05).The ICU hospitalization rate and intubation rate in the group C were lower than those in the group A and B,the differences were statistically significant(P<0.05).Conclusion:The respiratory humidification therapy apparatus combined with pulmonary rehabilitation therapy can significantly improve the respiratory function,restore the heart rate,reduce the ICU hospitalization rate and intubation rate,and promote the recovery of patients with COPD complicated with typeⅡrespiratory failure,which is worthy of promotion.
作者 林晓敏 涂智毅 苏国秋 邹天士 LIN Xiaomin;TU Zhiyi;SU Guoqiu;ZOU Tianshi(The First People’s Hospital of Zhaoqing,Guangdong Province,Zhaoqing 526000,China)
出处 《中国医学创新》 CAS 2022年第32期55-59,共5页 Medical Innovation of China
基金 肇庆市科技创新指导项目(190408104161580)。
关键词 呼吸湿化 肺康复 慢性阻塞性肺疾病 Ⅱ型呼吸衰竭 Respiratory humidification therapy apparatus Pulmonary rehabilitation Chronic obstructive pulmonary disease TypeⅡrespiratory failure
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